Evidence-driven manufacturing to expand pediatric cell therapy access in rare diseases

Active Other Transaction Agreement Awarded Last action

Contract number
140D042690013
Awardee
Awarding agency
Obligated
$6,842,620

Award facts

Contract value 100% obligated
$6,842,620.00 Current and potential, with all options
Completion date 31% complete
Current and potential, with all options
Funding agency
National Institutes of Health Department of Health and Human Services
NAICS code
Not on record
PSC
AN13 Health R&D Services; Health Care Services; Experimental Development
Competition
Program Solicitation
Pricing
Other
Place of performance
Los Angeles, CA 90033, USA

Award details come from SAM.gov/FPDS.

About this award

The National Institutes of Health (NIH) awarded the University of Southern California an Other Transaction Agreement valued at $6.84M on February 27, 2026, for "Evidence-Driven Manufacturing to Expand Pediatric Cell Therapy Access in Rare Diseases," with completion targeted for March 31, 2028. This civilian research contract will be performed in Los Angeles, California, and represents NIH's investment in expanding access to advanced cell therapy treatments for pediatric patients with rare diseases through evidence-based manufacturing approaches. USC, a leading private research institution with extensive experience managing federal contracts and grants across healthcare, scientific research, and defense domains, will serve as the prime contractor with no designated set-asides, allowing open competition for subcontracting opportunities.

This award leverages USC's substantial capabilities in biomedical research and development, particularly its experience with cell engineering and therapeutic innovation as demonstrated through its current federal grant portfolio, which includes $1.99M in NIH funding for in vivo cell engineering approaches to HIV cure development. The Other Transaction Agreement structure provides flexibility in execution and allows USC to apply specialized expertise in pediatric cell therapy manufacturing while generating evidence to support broader clinical implementation and regulatory pathways. The contract reflects NIH's commitment to advancing pediatric rare disease treatments through rigorous, data-driven manufacturing methodologies that could improve patient access and outcomes in this underserved patient population.

Quick answers

Who was awarded contract 140D042690013?

140D042690013 was awarded to University Of Southern California by Interior Business Center (Office of Policy Management and Budget) on February 27, 2026.

How much is contract 140D042690013 worth?

The government has obligated $6,842,620 on 140D042690013.

Which agency awarded contract 140D042690013?

Interior Business Center (Office of Policy Management and Budget) awarded 140D042690013, with funding from National Institutes of Health (Department of Health and Human Services).

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