Advanced analysis for precision cancer therapy multi-modal analysis with xnat (adapt max)

Active Other Transaction Agreement Awarded Last action

Contract number
140D042590022
Awardee
Awarding agency
Obligated
$4,484,079

Award facts

Contract value 75% obligated
  • $4,484,079.00 Current, with exercised options
  • $5,957,247.00 Potential, with all options
Completion date 24% complete
  • Current, with exercised options
  • Potential, with all options
Funding agency
National Institutes of Health Department of Health and Human Services
NAICS code
Not on record
Competition
Competed Program Solicitation
Pricing
Other
Place of performance
University City, MO 63130, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00002 · Wustl - adapt max | adapt $0
Other Administrative Action P00001 · WU - adapt max | adapt $0
Original award $4,484,079

About this award

The National Institutes of Health awarded an Other Transaction Agreement to The Washington University for $5,957,247 on May 20, 2025, to develop ADAPT MAX, an advanced multi-modal analysis platform for precision cancer therapy integrated with XNAT. This OTA sits outside the FAR and represents a prototype and research development effort under the statutory authority governing federal OTA awards.

The agreement extends through May 19, 2031. Work is performed in University City, Missouri. The platform will enable adaptive clinical trials for cancer treatments deployed within ARPA-H's ADAPT clinical trials, with the potential to increase trial effectiveness by adapting protocols to patient-specific disease pathways. ADAPT MAX comprises three integrated modules developed on XNAT and Microsoft's cloud-based data lake and AI services: the Portal for centralizing and sharing trial data, protocols, and resources; the Foundry, a web-based data science workbench for developing and validating data fusion techniques and computational biomarkers; and the Navigator, a clinician-facing environment for deploying biomarkers and treatment protocols for real-time patient treatment planning.

Embark Labs, LLC serves as a key subrecipient, developing software components including the Integrator, Foundry, and Navigator modules, with support from XNAT Works, Inc. Washington University investigators will provide operational and support services required to execute the ADAPT trials successfully.

Subawards

Subcontractor Amount Awarded
Embark Labs, LLC ADVANCED ANALYSIS FOR PRECISION CANCER THERAPY MULTI-MODAL ANALYSIS WITH XNAT (ADAPT MAX) Scope of Work Subrecipient: Embark Labs, Inc. – Kate Alpert Project:… $1,640,065

Quick answers

Who was awarded contract 140D042590022?

140D042590022 was awarded to The Washington University by Interior Business Center (Office of Policy Management and Budget) on May 20, 2025.

How much is contract 140D042590022 worth?

The government has obligated $4,484,079 on 140D042590022. Its potential value, with all options, is $5,957,247.

Which agency awarded contract 140D042590022?

Interior Business Center (Office of Policy Management and Budget) awarded 140D042590022, with funding from National Institutes of Health (Department of Health and Human Services).

Was contract 140D042590022 competed?

The extent of competition for 140D042590022 was competed.

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