Crispr delivery and manufacturing innovation for minimal-COG cancer and HIV therapies via in vivo immune engineering

Active Other Transaction Agreement Awarded Last action

Contract number
140D042590005
Awardee
Awarding agency
Obligated
$15,910,690

Award facts

Contract value 40% obligated
  • $15,910,690.00 Current, with exercised options
  • $40,130,860.00 Potential, with all options
Completion date 18% complete
  • Current, with exercised options
  • Potential, with all options
Funding agency
National Institutes of Health Department of Health and Human Services
NAICS code
Not on record
Competition
Competed Program Solicitation
Pricing
Other
Place of performance
Marlborough, MA 01752, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00002 $0
Other Administrative Action P00001 $0
Original award $15,910,690

About this award

The National Institutes of Health awarded an Other Transaction Agreement to Global Life Sciences Solutions USA LLC for $40,130,860 to develop CRISPR delivery and manufacturing innovation for minimal-cost cancer and HIV therapies via in vivo immune engineering, with an award date of September 25, 2025.

The agreement runs through September 24, 2031 and is performed in Marlborough, Massachusetts. As an OTA, this agreement operates outside the Federal Acquisition Regulation and represents a mechanism for advanced research and development collaboration with industry. Global Life Sciences Solutions, a wholly owned subsidiary of Danaher Corporation, specializes in advanced scientific equipment, chromatography systems, cell processing devices, and biological materials for federal research institutions. The company's core capability portfolio includes protein purification and chromatography systems, surface plasmon resonance instruments, controlled-rate freezers, cell processing equipment, and fluorescence imaging systems—technologies foundational to bioprocess innovation in cell and gene therapy manufacturing. This OTA reflects NIH's strategic focus on reducing manufacturing costs and improving delivery mechanisms for emerging immunotherapies targeting high-burden diseases.

Quick answers

Who was awarded contract 140D042590005?

140D042590005 was awarded to Global Life Sciences Solutions USA LLC by Interior Business Center (Office of Policy Management and Budget) on September 25, 2025.

How much is contract 140D042590005 worth?

The government has obligated $15,910,690 on 140D042590005. Its potential value, with all options, is $40,130,860.

Which agency awarded contract 140D042590005?

Interior Business Center (Office of Policy Management and Budget) awarded 140D042590005, with funding from National Institutes of Health (Department of Health and Human Services).

Was contract 140D042590005 competed?

The extent of competition for 140D042590005 was competed.

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