Acute and long-term effects of combined radiation and partial unloading on neurological and musculoskeletal systems in male and female rats
Ended Grant For Research Awarded Last action
- Contract number
- 80NSSC23K0774
- Awardee
-
Beth Israel Deaconess Medical Center, Inc. UEI C1CPANL3EWK4
- Awarding agency
-
Shared Services Center
National Aeronautics and Space Administration
- Obligated
- $825,957
Award facts
- Contract value 92% obligated
- $899,999.00 Current and potential, with all options
- Completion date 100% complete
- Current and potential, with all options
- Contracting staff
- NAICS code
- Not on record
- PSC
- AJ11 General Science And Technology R&D Services; General Science And Technology; Basic Research
- Set-aside
- No set-aside
- Competition
- Full and Open Competition Basic Research
- Pricing
- Other
- Place of performance
- Boston, MA 02215, USA
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Funding Only Action | $107,017 | |
| Funding Only Action | $144,000 | |
| Funding Only Action | $75,000 | |
| Funding Only Action | $175,000 | |
| Funding Only Action | $224,940 | |
| Other Administrative Action | $0 | |
| Original award | $100,000 |
About this award
Beth Israel Deaconess Medical Center, Inc., a Harvard Medical School-affiliated academic medical center located in Boston, Massachusetts, was awarded a $900K research grant on April 1, 2023, to investigate the acute and long-term effects of combined radiation and partial gravity unloading on neurological and musculoskeletal systems. The research will utilize male and female rats to evaluate separate and combined effects of simulated galactic cosmic rays and lunar gravity conditions (20% partial weight-bearing) on bone, muscle, and brain systems. The study will include assessments at 28 days to measure short-term effects and several months later to evaluate longer-term effects with recovery, employing functional, molecular, and histological evaluation methods. The research will be conducted at the facility's Boston location with simulated radiation exposure conducted at Brookhaven National Laboratory.
The contract is unfunded by the civilian defense or civilian shared services center and carries no set-aside designation. Work is scheduled for completion by May 31, 2026. This research directly supports NASA's Artemis Program lunar landing missions by providing critical data on how combined space radiation and reduced gravity environments affect human physiology, with particular attention to potential sex-specific differences relevant to the astronaut corps. The research team's established expertise in musculoskeletal and brain health, partial weight-bearing rodent models, and radiation exposure positions the institution to deliver actionable insights for human spaceflight applications.
Quick answers
Who was awarded contract 80NSSC23K0774?
80NSSC23K0774 was awarded to Beth Israel Deaconess Medical Center, Inc. by Shared Services Center (National Aeronautics and Space Administration) on April 1, 2023.
How much is contract 80NSSC23K0774 worth?
The government has obligated $825,957 on 80NSSC23K0774. Its current value, with exercised options, is $899,999.
Was contract 80NSSC23K0774 competed?
The extent of competition for 80NSSC23K0774 was full and open competition.
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