Grant For Research 80NSSC19K0467
- Not listed
- This is a $579,621.99 grant awarded by the National Aeronautics and Space Administration (NASA) to the University of California, San Diego (UCSD) to conduct research on the emergence of an RNA world. The grant supports two specific aims: 1) studying how prebiotically formed peptides may have influenced the rise and function of catalytic RNA ribozymes, and 2) investigating how nucleoside triphosphates could have been generated from free nucleosides and trimetaphosphate in an early RNA world...
- This is a $924,030.00 grant awarded by the National Aeronautics and Space Administration (NASA) to the Salk Institute for Biological Studies, a non-profit research institution located in La Jolla, California. The grant is part of NASA's effort to understand the origin of life on Earth, which will guide the search for life elsewhere in the universe. The research aims to construct RNA-based life in the laboratory, represented by populations of RNA enzymes that can catalyze their own replication...
- This is a research grant awarded by the National Aeronautics and Space Administration (NASA) to the University of California, Santa Barbara (UCSB) for the study of ribozymes and their evolvability. The $593,517.90 grant, part of NASA's Exobiology program, aims to map the fitness landscape of aminoacylation ribozymes to gain quantitative insights into their de novo emergence, optimization, and ability to evolve new functions. The research focuses on the potential role of ribozymes in the...
- This $1,514,000.00 grant was awarded by the National Aeronautics and Space Administration (NASA) to the University of California, San Diego (UCSD) to develop nano-optical methods for detecting chemical traces of life, with a focus on phosphorus, on returned space mission samples and meteorites. The award supports the use of nano-infrared imaging techniques to identify specific phosphorus-containing compounds that are critical for the origins of life. The research aims to enable highly precise,...
- This is a research grant awarded by the National Aeronautics and Space Administration (NASA) to the Foundation For Applied Molecular Evolution, Inc., a non-profit research organization, to support work related to understanding the origins of life. The $585,961 grant supports experimental research on the "RNA First" model for the prebiotic formation of RNA, building on the "Discontinuous Synthesis Model" (DSM) and exploring challenges that must be resolved for the DSM to be...
- This is a cooperative agreement awarded by the National Aeronautics and Space Administration (NASA) to The Regents of the University of California, San Francisco (UCSF) to investigate the role of RNA molecules in the origin of genetic systems. The $499,153 contract, awarded on July 13, 2016, is part of NASA's Evolutionary Mechanisms of Simple Genomes program and has a period of performance through July 12, 2019. The research aims to address fundamental questions about the early evolution of...
- The National Aeronautics and Space Administration (NASA) awarded a $210,000 grant to the University of California, San Diego (UCSD) to conduct research using advanced molecular biology tools to identify genes in the cyanobacterium Synechococcus elongatus that are critical for adapting to the spaceflight environment. The goal is to compare the growth and survivability of this photosynthetic microorganism between space and Earth conditions. This research aligns with NASA's priorities to understand...
- The National Aeronautics and Space Administration (NASA) awarded a $548,909.00 grant to the University of Washington (UW) to investigate how protocells composed of a membrane, RNA, and protein could have arisen on the early Earth. The research focuses on testing key elements of a scenario where the building blocks of RNA and protein were selected and concentrated via binding to fatty acid aggregates, which then stabilized the fatty acid membranes and facilitated polymerization. This work...
- This is a grant award from the National Aeronautics and Space Administration (NASA) Shared Services Center to The Salk Institute for Biological Studies, a non-profit research organization in San Diego, California. The $1,000,379.00 grant is for a project titled "EVOLUTION OF CATALYTIC RNA AND THE ORIGINS OF LIFE" with a period of performance through May 10, 2025. The grant supports fundamental biological research to investigate the molecular origins of life, particularly the role of...
- The National Aeronautics and Space Administration (NASA) awarded a $163,350.00 grant to the University of California, San Diego (UCSD) for research related to the origin, structure, and evolution of a particular material. This grant, which does not have a set-aside designation, is scheduled to be completed by April 26, 2025. UCSD, a public research university, will be the prime contractor on this effort. The State of California Controller's Office, a U.S. state government entity, is the parent...
The University of California, San Diego (UCSD), represented by its Office of Contract & Grant Administration, was awarded a $514,057 grant from the National Aeronautics and Space Administration (NASA) to investigate the conditions that could have led to the emergence of an early life form on Earth or other planets. The research will focus on the "RNA world hypothesis," which proposes that organisms using RNA as their genome and catalyst preceded today's DNA/RNA/protein-based life forms. The grant will fund studies on how larger ribozymes (catalytic RNA molecules) could have assembled from shorter RNA oligomers in a prebiotic environment, as well as how the size of ribozymes could have been reduced by fine-tuning RNA duplex stability. This research aligns with NASA's interests in understanding the "prebiotic evolution" of chemical systems that could have served as precursors to metabolic and replicating systems. The grant does not have a set-aside designation.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| P00003 | Other Administrative Action | $0 | 3/31/22 | |
| Not listed | $0 | 3/31/22 | ||
| P00002 | Funding Only Action | $180.2k | 4/8/21 | |
| Not listed | $180.2k | 4/8/21 | ||
| Not listed | $176.5k | 3/25/20 |