Grant For Research 80NSSC19K0437
- Not listed
- This is a $750,000.00 Cooperative Agreement awarded by the National Aeronautics and Space Administration (NASA) to the University of Arkansas at Little Rock (UALR), a member of the University of Arkansas System. The contract is not set aside for any socioeconomic program. The purpose of the contract is to test the hypothesis that cosmic ionizing radiation (CIR) and space microgravity (SMG) will cause immune system dysfunction, and that treatment with the compound tocoflexol will provide immune...
- This $179,871.47 federal grant award to Texas A&M University was issued by the National Aeronautics and Space Administration (NASA) to study the effects of space radiation and microgravity on the cardiovascular system. The research aims to understand how space flight imposes unique stressors on astronauts, particularly the damage and fibrosis that can occur in the heart and vasculature due to radiation exposure. The grant will fund a series of mouse studies using X-ray, heavy ion, and...
- This $540,200 cost-plus-fixed-fee grant was awarded by the National Aeronautics and Space Administration Shared Services Center to New York Medical College, a subsidiary of Touro University, to study the long-term consequences of cosmic radiation exposure. Over the three-year period of performance ending January 2023, the contractor will evaluate the impact of heavy ion radiation like iron-56 and protons on cardiovascular function and identify pathways that lead to radiation-induced...
- This is a $947,315.00 grant awarded by the National Aeronautics and Space Administration (NASA) to The Research Foundation for the State University of New York (Stony Brook University) to test the efficacy of the dietary supplement apigenin (AP) for preventing and mitigating cancer due to space radiation exposure. The primary goal is to investigate whether AP can suppress radiation-induced inflammation and oxidative stress during the initiation and promotion stages of carcinogenesis. The study...
- This is a $2,478,052.00 grant award from the National Aeronautics and Space Administration (NASA) to the University of Texas Southwestern Medical Center (UT Southwestern) in Dallas, Texas. The grant is part of NASA's "MOUSE MODELS OF CANCER RISK AND PREVENTION FROM SPACE RADIATION" program and supports research on the molecular effects of low-dose space radiation exposure. The objective is to use mouse models to understand how different types and doses of radiation impact the...
- Texas A&M AgriLife Research, a research division of the Texas A&M University System, was awarded a grant valued at approximately $600K to investigate telomere dynamics and oxidative stress in Arabidopsis within the space radiation environment. The research project, designated 21-21SBPS_2-0029, commenced on November 21, 2022, with completion expected by November 20, 2026, and will be conducted at the awardee's facility in College Station, Texas. No set-aside designation was applied to...
- The National Aeronautics and Space Administration (NASA) awarded a $150,000 grant to the University of Arizona (doing business as the Arizona Board of Regents) to conduct research on the effects of simulated microgravity on the anti-tumor activity of human natural killer (NK) cells and gamma-delta T (GD-T) cells in a humanized mouse model. The goal is to determine if impaired immune system function during long-duration spaceflight could increase cancer and viral infection risks for exploration...
- Duke University's Office of Research Administration has been awarded an $800,000 research grant by the NASA Shared Services Center, with a completion date of November 30, 2026. This non-set-aside grant supports a multi-disciplinary investigation into the cardiovascular effects of environmental stressors encountered during space exploration, specifically examining the individual and combined impacts of galactic cosmic radiation and weightlessness on cardiac biology. The research leverages two...
- This federal contract award, valued at $99,923.61, was issued by the National Aeronautics and Space Administration (NASA) to Texas A&M University to investigate the impact of a diet high in omega-3 fatty acids on mitigating radiation-induced bone loss. The research aims to determine if this dietary intervention can reduce the generation of inflammatory cytokines in bone tissue, which have been linked to accelerated bone resorption and suppression of bone formation in astronauts exposed to...
- The Trustees of Columbia University in the City of New York, doing business as Health Sciences Division, was awarded a $149,834.28 grant by the National Aeronautics and Space Administration (NASA) to conduct biomedical research on the bioactive proteins secreted by the human vasculature in response to low-dose space radiation. The original research aims remain unchanged, with the exception of re-numbering and modifying the irradiation plan to include gamma and mixed field exposures instead of...
The University of Arkansas for Medical Sciences (UAMS) was awarded a $965,940 research grant by a civilian federal agency to investigate gamma-tocotrienol as a countermeasure against high-energy charged particle-induced carcinogenesis, cardiovascular disease, and central nervous system effects. The project, designated 17-BPBA_2-0092, will utilize 366 genetically modified TRP53ΔP/ΔP mice obtained from an in-house breeding colony at UAMS, with breeders provided by collaborators at the University of California, San Francisco. The research involves two specific aims: the first will evaluate the efficacy of gamma-tocotrienol in preventing radiation-induced cancer by exposing 210 mice to simulated galactic cosmic radiation at Brookhaven National Laboratory's NASA Space Radiation Laboratory, administering gamma-tocotrienol via subcutaneous injection prior to each radiation fraction, and conducting an 18-month tumor surveillance follow-up at Colorado State University. The second aim will utilize an additional 60 mice to obtain plasma samples at designated intervals following gamma-tocotrienol administration to assess pharmacokinetic parameters. The award, which commenced on January 31, 2019 and concludes on October 31, 2025, is structured as a research grant with no small business set-aside designation. The project will involve multiple collaborative institutions including the University of Florida for gamma-tocotrienol purification, Brookhaven National Laboratory for radiation exposure, and Colorado State University for long-term tumor monitoring and pathological analysis. This research represents a critical investigation into potential protective agents against space radiation exposure, with implications for astronaut health and occupational safety in radiation environments.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $85.1k | 11/18/25 | ||
| P00012 | Funding Only Action | $85.1k | 11/18/25 | |
| Not listed | ($77k) | 5/13/25 | ||
| P00011 | Funding Only Action | ($77k) | 5/13/25 | |
| Not listed | $0 | 9/18/24 |