Grant For Research 80NSSC19K0436
- Not listed
- The National Aeronautics and Space Administration (NASA) awarded a $115,332.01 research grant to Temple University-Of The Commonwealth System Of Higher Education, doing business as Temple University, to study the potential cardiovascular effects of ionizing space radiation exposure on astronauts during long-duration space missions to the Moon and Mars. The grant aims to determine qualitative differences and quantify radiobiological effective thresholds for biological damage induced by various...
- The Trustees of Columbia University in the City of New York, doing business as Health Sciences Division, was awarded a $149,834.28 grant by the National Aeronautics and Space Administration (NASA) to conduct biomedical research on the bioactive proteins secreted by the human vasculature in response to low-dose space radiation. The original research aims remain unchanged, with the exception of re-numbering and modifying the irradiation plan to include gamma and mixed field exposures instead of...
- Duke University's Office of Research Administration has been awarded an $800,000 research grant by the NASA Shared Services Center, with a completion date of November 30, 2026. This non-set-aside grant supports a multi-disciplinary investigation into the cardiovascular effects of environmental stressors encountered during space exploration, specifically examining the individual and combined impacts of galactic cosmic radiation and weightlessness on cardiac biology. The research leverages two...
- This federal contract award was issued by a civilian agency, the Shared Services Center, to the Icahn School of Medicine at Mount Sinai (ISMMS) on April 10, 2019. The $3,611,251.77 grant contract is for research to address gaps in NASA's Human Research Program (HRP) Integrated Research Plan related to the risk of cardiovascular disease and other degenerative tissue effects from radiation exposure. The research aims to develop tissue-specific experimental models, understand mechanisms of...
- This $179,871.47 federal grant award to Texas A&M University was issued by the National Aeronautics and Space Administration (NASA) to study the effects of space radiation and microgravity on the cardiovascular system. The research aims to understand how space flight imposes unique stressors on astronauts, particularly the damage and fibrosis that can occur in the heart and vasculature due to radiation exposure. The grant will fund a series of mouse studies using X-ray, heavy ion, and...
- This is a $300,000.00 grant awarded by the National Aeronautics and Space Administration (NASA) to The Ohio State University to conduct research on reducing the uncertainty in estimates of cancer and cardiovascular risks from space radiation. The study will evaluate changes in molecular biomarkers in rodents and rabbits exposed to radiation relevant to astronaut exposures. Archived tissue samples will be analyzed using modern analytical technologies and rigorous statistical methods to examine...
- This is a $2,773,956 grant awarded by the National Aeronautics and Space Administration (NASA) to Loma Linda University (LLU), a private, non-profit educational institution in California. The grant is for the "Definition Phase Only" of research to study the effects of space radiation on the central nervous system. LLU will expose adult mice to various charged particle mixtures found in space, including protons, helium, oxygen, and silicon, at different dose rates over long time...
- This is a $60,000.00 grant awarded by the National Aeronautics and Space Administration (NASA) to the Weill Medical College of Cornell University, a prestigious academic medical institution, for a research project titled "SPACEFLIGHT AND REGOLITH INDUCED MITOCHONDRIAL STRESS MITIGATED BY MIRNA-BASED COUNTERMEASURES". The grant is intended to support research focused on understanding and mitigating the effects of spaceflight and lunar regolith exposure on mitochondrial stress, using...
- This federal contract award, valued at $2,089,751.30, was granted to The Medical College of Wisconsin, Inc. (MCW) to conduct research on the effects of microgravity and space radiation on cardiac disease. The award is intended to address key aspects of the research goals outlined in Topic 6 of the National Research Announcement (NRA) NNJ16ZSA001N-SRHHC, which focuses on Space Radiation and Human Health Countermeasures. The proposed research aims to 1) provide detailed physiological and...
- This is a three-year grant awarded by the National Aeronautics and Space Administration (NASA) to the National Council on Radiation Protection and Measurements (NCRP), a non-profit organization based in Bethesda, Maryland. The grant is for an in-depth study to more fully understand the risk of central nervous system (CNS) effects following radiation exposures in space and to provide guidance for risk management and radiation protection. The grant is a follow-on to a previous Phase 1 effort...
This $540,200 cost-plus-fixed-fee grant was awarded by the National Aeronautics and Space Administration Shared Services Center to New York Medical College, a subsidiary of Touro University, to study the long-term consequences of cosmic radiation exposure. Over the three-year period of performance ending January 2023, the contractor will evaluate the impact of heavy ion radiation like iron-56 and protons on cardiovascular function and identify pathways that lead to radiation-induced cardiomyopathy. The contractor will utilize cultured cells and mouse models to test the effectiveness of three countermeasures - Mitotempo, Metformin, and Lisinopril - at mitigating cellular damage, accelerated senescence, and genomic instability caused by space radiation. Findings from this research aim to improve understanding of space radiation risks and inform strategies to ensure the long-term health of crew members on deep space missions beyond low Earth orbit.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($48k) | 1/9/24 | ||
| P00006 | Funding Only Action | ($48k) | 1/9/24 | |
| Not listed | $0 | 12/14/21 | ||
| P00005 | Other Administrative Action | $0 | 12/14/21 | |
| Not listed | $0 | 8/3/21 |