Preclinical toxicology of large molecule drugs developed for cancer and other indications

Active Definitive Contract Awarded Last action

Contract number
75N91022C00010
Awardee
Awarding agency
Obligated
$3,452,984

Award facts

Contract value 37% obligated
  • $4,538,201.00 Current, with exercised options
  • $9,353,817.00 Potential, with all options
Completion date 65% complete
  • Current, with exercised options
  • Potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 4 offers Negotiated Proposal / Quote
Pricing
Cost Plus Fixed Fee
Place of performance
Chicago, IL 60616, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Funding Only Action P00014 · EO14398 preclinical toxicology of large molecule drugs developed for cancer and other indications $549,996
Exercise an Option P00013 $10,000
Exercise an Option P00012 $10,025
Other Administrative Action P00011 $0
Funding Only Action P00010 $375,416
Exercise an Option P00009 $300,728
Other Administrative Action P00008 $0
Other Administrative Action P00007 $0
Funding Only Action P00006 $676,819
Funding Only Action P00005 $0
Other Administrative Action P00004 $0
Exercise an Option P00003 $309,267
Other Administrative Action P00002 $470,733
Funding Only Action P00001 $675,000
Original award $75,000
Show all 15

About this award

The National Cancer Institute awarded a $9.35 million definitive contract to IIT Research Institute for preclinical toxicology of large molecule drugs developed for cancer and other indications on April 1, 2022, under cost-plus-fixed-fee pricing with no set-aside.

The originating solicitation addresses preclinical toxicology studies supporting investigational new drug development, aligned with Executive Order 14398 priorities. Place of performance is Chicago, IL. The contract runs through March 31, 2029.

IIT Research Institute is a non-profit contract research organization and wholly-owned subsidiary of Illinois Institute of Technology, operating exclusively as a prime contractor on federal preclinical drug development and toxicology research services to the National Institutes of Health ecosystem. The organization conducts Good Laboratory Practice and non-GLP toxicology studies in rodent and canine models, dose range-finding evaluations, pharmacokinetic analyses, and safety assessments for small molecule and biologic drug candidates.

Service Contract Inventory reporting for this contract shows FY2025 labor activity of 0.2 FTEs with no subcontractor involvement; the prime self-performed all reported work. Prior-year invoiced activity included $164 thousand in FY2023 across 18 contractor hours, reflecting periodic study milestones rather than continuous staffing. This contract represents one ordering vehicle within IIT Research Institute's broader $149.995 million multiple-award PREVENT Cancer Preclinical Drug Development Program IDIQ with NCI, which covers preclinical efficacy evaluation, analytical testing, process development, and toxicological testing of cancer preventive agents.

Quick answers

Who was awarded contract 75N91022C00010?

75N91022C00010 was awarded to IIT Research Institute by National Cancer Institute (National Institutes of Health) on April 1, 2022.

How much is contract 75N91022C00010 worth?

The government has obligated $3,452,984 on 75N91022C00010. Its current value, with exercised options, is $4,538,201. Its potential value, with all options, is $9,353,817.

Was contract 75N91022C00010 competed?

The extent of competition for 75N91022C00010 was full and open competition. The government received 4 offers.

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