Topic 372: development and validation of non-mouse reagents to enable preclinical development of novel therapeutics

Ended Definitive Contract Awarded Last action

Contract number
75N91020C00018
Awardee
Awarding agency
Obligated
$1,995,852

Award facts

Opportunity
  • BAA75N91019R00032 Solicitation number
Contract value 100% obligated
$1,995,852.00 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
Set-aside
Total Small Business
Competition
Full and Open Competition after exclusion of sources · 1 offer Negotiated Proposal / Quote
Pricing
Firm Fixed Price
Place of performance
San Diego, CA 92121, USA
Research
SBIR Program Phase II Action
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00006 $0
Supplemental Agreement for work within scope P00005 $0
Supplemental Agreement for work within scope P00004 $0
Other Administrative Action P00003 $0
Change Order P00002 $0
Other Administrative Action P00001 $0
Original award $1,995,852

About this award

This is a $1,995,852.00 Firm Fixed Price SBIR Phase II contract awarded by the National Cancer Institute (NCI) to Avantgen Inc., a small business based in San Diego, California. The contract is for the "Development and Validation of Non-Mouse Reagents to Enable Preclinical Development of Novel Therapeutics" under Topic 372. The goal is to develop high-affinity, highly specific rabbit monoclonal antibodies against an expanded panel of 26 canine biomarkers to facilitate the use of dogs with naturally occurring cancers as a better model system for evaluating novel cancer immunotherapies. Avantgen will also optimize a caninized anti-canine-PD-1 antibody as a potential canine immunotherapeutic and conduct a pilot study in pet dogs with lymphoma. Duke University is a major subcontractor supporting this effort.

Quick answers

Who was awarded contract 75N91020C00018?

75N91020C00018 was awarded to Avantgen Inc. by National Cancer Institute (National Institutes of Health) on September 16, 2020.

How much is contract 75N91020C00018 worth?

The government has obligated $1,995,852 on 75N91020C00018.

Was contract 75N91020C00018 competed?

The extent of competition for 75N91020C00018 was full and open competition after exclusion of sources. The government received 1 offer. It was set aside: Total Small Business.

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