Malaria Culture Service
Closed Pre-Solicitation Posted
- Solicitation number
- NIHDA201800271
- Agency
- National Institutes of Health Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- Contract number
- 75N95018P00552 Federal contract award
- NAICS code
- 325414 Biological Product (except Diagnostic) Manufacturing
- PSC
- Not on record
- Place of performance
- National Center for Advancing Translational Sciences 9800 Medical Center Drive Rockville, Maryland 20850, United States
Notice details come from SAM.gov. Updated .
Notice text
2 versions
Update #2 · Latest ·
NON-COMPETITIVE
COMBINED SYNOPSIS / SOLICITATION
Title: Malaria Culture Service
(i) This is a non-competitive combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.
(ii) The solicitation number is NIHDA201800271 and the solicitation is issued as a request for proposals (RFP).
This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5- Simplified Procedures for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is expected to exceed the simplified acquisition threshold.
THIS IS A NON-COMPETITIVE (NOTICE OF INTENT) COMBINED SYNOPSIS SOLICITATION TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME).
The National Institute on Drug Abuse (NIDA) Office of Acquisitions, NCATS Section, on behalf of the National Center for Advancing Translational Sciences (NCATS),intends to negotiate and award a contract without providing for full and open competition (including brand-name) to Sanaria, Inc., 9800 Medical Center Drive, Suite A209, Rockville, MD 20850, for a 24 month malaria culture service that will provide asexual blood stage cultures and medium on a monthly basis, and enriched late stage gametocyte cultures, blood, and medium on a quarterly basis.
This acquisition is conducted as non-competitive for a commercial item or service and is conducted under the authority of the FAR Subpart 13.5-Simplified Procedures for Certain Commercial Items and 13.501 Special documentation requirements and the authority of 41 U.S.C. 1901 and 41 U.S.C. 3304.
Pursuant to FAR Subpart 13.501 (a) (1) (iii) the justification (excluding brand name) will be made available within 14 days after contract award or in the case of unusual and compelling urgency within 30 days after contract award.
(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-99-1 dated 7-16-2018.
(iv) The associated NAICS code is 325414 and the small business size standard is 1250 employees. The requirement has no set-aside restrictions.
(v) Purpose and Objectives: The scope of this work is for a 24 month malaria culture service that will provide asexual blood stage cultures and medium on a monthly basis, and enriched late stage gametocyte cultures, blood, and medium on a quarterly basis..
(vi) Proposals must meet the requirements for the malaria cultures, including delivery and reporting, described in the attached Statement of Work dated July 2, 2018.
(vii) Performance will take place for 24 months beginning after receipt of award, with delivery at NCATS, 9800 Medical Center Drive, Rockville, MD 20850.
(viii) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition
(ix) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, applies to this acquisition.
(a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: technical (technical capability of the item offered to meet the Government requirement; staff expertise, including their availability, experience, and formal and other training; current in-house capability and capacity to perform the work; whether and how shipping/delivery of the cultures can be accomplished, with regard to viability of the shipped cultures, integrity of results, and safety; prior completed projects of similar nature; and corporate experience and management capability); past performance; and price. Technical and past performance, when combined, are significantly more important than cost or price.
(b) Options. The Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic requirement. The Government may determine that an offer is unacceptable if the option prices are significantly unbalanced. Evaluation of options shall not obligate the Government to exercise the option(s).
(c) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer's specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award.
(x) The Offerors to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications-Commercial Items, with its offer.
(xi) The FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition.
(xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition and is attached.
(xiii) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition
(xiv) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations.
In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov."
All responses must reference solicitation number NIHDA201800271. Responses must be submitted electronically to Stuart Kern, Contract Specialist, stuart.kern@nih.gov.
Fax responses will not be accepted.
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Update #1 ·
This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.
This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only.
Background: Malaria affects an estimated 250 million people worldwide, particularly in the tropical regions of Sub-Saharan Africa and approximately 650,000 patients die each year. Even while on current therapies, patients remain infectious for a period of time, allowing further mosquito-borne transmission to others.
Control of parasite transmission is critical for elimination and eradication of malaria. However, most antimalarial drugs are not active against sexual stage P. falciparum parasites - called gametocytes - which are responsible for the spread of malaria from person to person via mosquitoes. Torin2 was identified as a lead molecule in a new class of gametocytocidal antimalarial drugs.
As part of a lead optimization program, researchers are using a gametocyte viability assay, as well as an asexual stage parasite assay to optimize the Torin2 series and advance a drug candidate through pre-clinical development and early clinical development.
Purpose and Objectives: The scope of this work is for a 24 month malaria culture service that will provide asexual blood stage cultures and medium on a monthly basis, and enriched late stage gametocyte cultures, blood, and medium on a quarterly basis..
Project requirements: Monthly asexual stage parasites and quarterly provision of Plasmodium falciparum enriched gametocytes for use in viability assays:
1. Plasmodium falciparum asexual parasites (20 mL), with ring stages >90%.
2. Complete medium (100mL) for asexual parasites.
3. Plasmodium falciparum enriched gametocytes (5 mL), stage IV-V >70%. 4-5X10^7 gametocytes/ml
4. 50% Blood (1-5 mL).
5. Complete medium (100mL) for enriched gametocytes.
Anticipated period of performance: 24 months, beginning after receipt of award.
Other important considerations: See the attached Statement of Work for detailed descriptions of the deliverables, acceptance criteria, and reporting requirements.
Capability statement /information sought. Respondents must provide, as part of their responses, a capability statement or other information regarding respondents': (a) staff expertise, including their availability, experience, and formal and other training; (b) current in-house capability and capacity to perform the work; (c) how shipping/delivery of the cultures can be accomplished, with regard to viability of the shipped cultures, integrity of results, and safety; (d) prior completed projects of similar nature; (e) corporate experience and management capability; and (f) examples of prior completed Government contracts, references, and other related information.
The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements.
One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2" x 11" paper size, with 1" top, bottom, left and right margins, and with single or double spacing.
The information submitted must be must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required.
The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested.
The response must include the respondents' technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.
All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted.
The response must be submitted to Stuart Kern, Contract Specialist, stuart.kern@nih.gov.
The response must be received on or before July 11, 2018, at 4:00 p.m., Eastern time.
Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work.
Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.
Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
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Attachments
| File | Type | Posted |
|---|---|---|
| 6.4947338_FAR_52.212-5_(Jan_2018).pdf | ||
| invoice_instructions_sat_508_NIH_OFM.pdf | ||
| 6.4947338_SOW_Malaria.pdf | ||
| SOW_Malaria.pdf |
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