Notice of Intent to SS.pdf

PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS

INTRODUCTION

THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT)

SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT

PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME).

The National Heart, Lung, and Blood Institute (NHLBI), Office of Acquisitions (OA) on behalf of the National Institute of Dental and Craniofacial Research intends to negotiate and award a Purchase Order without providing for full and open competition (Including brand-name) to Becton, Dickinson and Company at One Becton Drive Franklin Lakes, NJ 07417 for a Florescence Activated Cell Sorting System.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 334516 Analytical Laboratory Instrument Manufacturing with a small business Size Standard of 1000 employees.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2020-06 effective 06-05-2020.

This acquisition is conducted under the procedures as prescribed in FAR subpart 13.5—Simplified Procedures for Certain Commercial Items and FAR subpart 12— Acquisition of Commercial Items at an amount exceeding the SAT, and not exceeding $7 million.

STATUTORY AUTHORITY

This acquisition is for a commercial item or service and is conducted under the authority of the FAR Subpart 13.5—Simplified Procedures for Certain Commercial Items, section 4202 of the Clinger-Cohen Act of 1966) and the statutory authority of FAR 6.302-1- Only one responsible source and no other supplies or services will satisfy agency requirements 41 U.S.C. 253(c)(1).

DESCRIPTION OF REQUIREMENT

Background Research in the NIDCR Intramural Research Program revolves around five main research areas: Craniofacial Developmental, Cell and Matrix Biology; Epithelial and

Salivary Gland Biology and Dysfunction; Immunology and Inflammation; Sensory Biology; and Skeletal Biology. Within these research areas, our scientists are tasked with elucidating the molecular mechanisms that underlie a plethora of biological processes as they relate to both basic research and disease manifestations in a clinical setting.

The Combined Technical Research Core (CTRC) provides essential Flow Cytometry analysis and Florescence Activated Cell Sorting (FACS) services to the entire NIDCR/DIR and its collaborators.

Purpose and Objectives The laboratory requires a high dimensional FACS system for single cell isolation.

Period of Performance Delivery within 90-120 days after award Firm-Fixed Price Type Contract

Project Description The instrument shall accommodate high parameter cell sorting demands and safe single cell sigh-content high-parameter cellular including human cell sorting capabilities.

The instrument shall be a FACSymphony S6 High Parameter SORP cell sorter or equivalent, a bench-top high speed cell sorter equipped with five lasers (355, 405, 488, 561, and 637nm) capable of analyzing up to 30 different colors plus forward and side scatter. The instrument shall include the following or equivalent:

The system shall meet these hardware specifications:

A. The capability of up to 9 lasers, 60 parameters with 58 colors.

B. State of the art fiber optics to carry the light/fluorescent signal from the flow cell to the photomultiplier tube detectors (PMTs.)

C. The option of tube, APD or Silicon Chip detectors based on maximum channel sensitivity with each type.

D. Decagon optical arrangement for lasers.

E. Air-cooled lasers.

F. Fixed alignment optics in conjunction with solid state lasers ranging in power from 60mW to 1000mW.

G. Easily replaceable optical filters and mirrors for experimental flexibility.

H. No special room requirements (no special electrical requirements, no special plumbing requirements, and no special air requirements).

I. Sensitivity of <15 MESF-PE and <50 MESF-FITC.

J. Provide for performing real-time statistics via the DIVA software.

K. Class II Biosafety cabinet with integrated safety interlocks.

L. Quantiflash LED Integrated Pulser QC tool.

M. Capability of analyzing at least 30 logical gates.

N. State of the art low noise digital acquisition electronics with acquisition speeds of

40000 events per second.

O. Six-way high speed sorting and single cell deposition into 96 and 384well microtiter plates

The system shall meet these software specifications:

A. Capability of integrated Laser Control Software which allows the user to adjust laser power up or down on an as needed basis.

B. Shall be software compatible with existing laboratory (BD Diva) and institute high parameter cytometers for ease of transition of existing experimental protocols and minimum operator training.

Product Number Description UOM QTY

662937 00382906629371

FACSymphony S6 Special Order System

EA 1

340345 00382903403455

BD FACS Clean Solution 5L

EA 1

345249 00382903452491

Accudrop Fluorescent Beads 25 Tests

EA 1

340486 00382903404865

Calibrite 3 Color Beads Kit 25 Tests IVD

EA 1

340487 00382903404872

Calibrite APC Beads 25 Tests IVD

EA 1

556291 00382905562914

Rainbow Flrs Prtcl Bright 3.0-3.4um 5mL

EA 1

655050 00382906550507

BD FACSDiva CS&T Research Beads Kit 50T

EA 3

99-30211-00 BD FACSflow Sheath Fluid 20L

EA 2

625838 00382906258380

HIGH

PARAMETER

IMMUNOLOGY

PANEL

EA 1

657590 00382906575906

Option Hood Safety Biological

EA 1

643154 00382906431547

Aria II Temperature Control Option 115V

EA 1

566352 00382905663529

HPS Fluorochrome Evaluation Kit

EA 1

624371 00382906243713

HPS Prototype Fluorochrome Eval Kit

EA 1

660360 00382906603609

Compressor Air

EXT120V/60HZ 0-

120Psi 4L

EA 1

Other specifications:

A. Shall be compatible with the existing FACS Analyzer BD Symphony for transition of experimental protocols and templates.

B. Shall be compatible to permanently be integrated in a Baker Class II Type A2 biosafety hood.

Other Requirements:

• Shall provide user training.

• Shall have a proven user base with service support guaranteed within 48 hours.

Delivery:

• The Contractor shall deliver and install the equipment within 90-120 days after receipt of order. Delivery must be Freight on Board (FOB) Destination and include inside delivery. On-site training must take place within four (4) weeks of equipment installation. The equipment shall be delivered and installed in coordination with the Contracting Officer’s Representative (COR). The contractor shall provide an Original Equipment Manufacturer (OEM) certified service technician to perform setup, installation, and an on-site training session for staff members.

Warranty:

• The Contractor shall warrant that the all equipment will be free from defects for a period of at least twelve (12) months from the date of installation, inspection by the Government, and acceptance.

Other Important Considerations

1. No refurbished equipment will be accepted.

2. The items must be brand name or equal equivalent with the “BD FACSymphony S6” Number and Product Description

3. On-site installation must be performed during normal business hours and under the supervision of laboratory personnel by technicians trained and certified in this equipment installation and set-up, such that warranties are not voided and future maintenance and upgrades can be performed under current service contracts

CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION

(INCLUDING BRAND-NAME) DETERMINATION

The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted as prescribed in FAR Part 10—Market Research, specifically the review and evaluation of the responses to the sources sought notice published in the FedBizOpps and FedConnect on May 15, 2020 for a period of ten (10) days via Solicitation 75N92020Q0085 titled Florescence Activated Cell Sorting System.

The initial market research conducted by the program office provided a quote from Becton, Dickinson and Company, which is a large business manufacturer of the cell sorter equipment. The market research conducted by the contract specialist also provided the same result for the large business equipment manufacturer via Google search. There were no other sources located through the SBA Quick Market Search, GSA eLibrary, GSA Advantage, or the NIH Contract Directory. The FPDS-NG search yielded one result, the manufacturer Becton, Dickinson and Company. In addition, a sources sought notice was posted on May 15, 2020 for a period of ten (10) days which yielded no responses. No small businesses were located.

The features of this equipment are necessary to perform florescence activated cell sorting experiments and are not found among other brands.

CLOSING STATEMENT

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (betaSAM) https://beta.sam.gov.”

A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All responses must be received by [ 07/01/2020 at 12:00 PM EST]. Responses must be submitted via the FedConnect webportal (www.fedconnect.net). Potential Offerors do not need to register to view a notice; however, in order to submit questions and/or response to this Notice, an account will need to be established. Should you require a waiver not to use FedConnect, please contact the Contracting Officer listed in this notice.

“All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency.”

https://beta.sam.gov/ http://www.fedconnect.net/

All responses must be received by [ 07/01/2020 at 12:00 PM EST]. Responses must be submitted via the FedConnect webportal (www.fedconnect.net). Potential Offerors do not need to register to view a notice; however, in order to submit questions and/or r...