Digital_PCR_RFQ_-_FBO_(2).docx

Two (2) Digital PCR Systems - Request for Quotes

The Uniformed Services University of the Health Sciences (USU) is the Nation's federal health sciences university and is committed to excellence in military medicine and public health during peace and war. We provide the Nation with health professionals dedicated to career service in the Department of Defense and the United States Public Health Service and with scientists who serve the common good. We serve the uniformed services and the Nation as an outstanding academic health sciences center with a worldwide perspective for education, research, service, and consultation; we are unique in relating these activities to military medicine, disaster medicine, and military medical readiness. USU is located in Bethesda, MD on the grounds of the Naval Support Activity Bethesda.

Additional information regarding USU can be found on our website: www.usuhs.mil.

USU has a requirement for Two (2) Digital PCR Systems, to include four (4) one (1) year options for maintenance.

This is a combined synopsis/solicitation for commercial items in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. This is a request for quotes (RFQ) for commercial items in accordance with the procedures of FAR Part 12 - Acquisition of Commercial Items and FAR Part 13 - Simplified Acquisition Procedures, to include FAR Subpart 13.5, Test Program for Certain Commercial Items, in accordance with the class deviation titled “Permanent Authority for Use of Simplified Acquisition Procedures for Certain Commercial Items” (DARS Tracking Number 2015-O0004). This RFQ incorporates all provisions and clauses in effect through Federal Acquisition Circular (FAC) 05-81 (April 10, 2015) and Defense Federal Acquisition Regulation Supplement (DFARS) (April 20, 2015).

In order to be eligible for award, offerors must be registered in www.SAM.gov, with completed representations and certifications by the close date of the solicitation.

Offerors interested in responding to this requirement must provide a quote for Two (2) Digital PCR Systems, which at a minimum, meets the specifications listed below. One or more firm fixed-priced (FFP) orders will be awarded. Offerors are encouraged to submit multiple quotes for Digital PCR Systems which will be evaluated separately by the Government.

Desired Specifications:

DIGITAL PCR SYSTEMS - DESIRED SPECIFICATIONS

· Absolute quantification of target single DNA or RNA molecules

· State of the art methodology for dye and probe based PCR quantification analysis

· Capacity to partition each sample at least 20,000 fold

· Rapid sample partitioning time (<5 minutes)

· Ability to multiplex sample amplification (at least 48 samples)

· Rapid sample read time (< 30 minutes)

· Rare event detection (1 in 10,000)

· Ability to assay from SYBR-based reactions

· Does not require calibrating sample

· Utilizes consumables from various sources

· Multi-User platform

System should support the following applications:

· Rare DNA target identification and quantification

· Pathogen detection

· Absolute quantification of sequencing libraries

· Digital gene expression analysis for low abundance transcripts

· Genotyping and copy number variation detection

· Next-generation sequencing (NGS)

· Biomarker detection and validation

· Single cell mRNA analysis

The selected offeror will be required to provide installation and training. The resultant award(s) will include four (4) one year option periods for maintenance, with the first option period beginning the day after the warranty expires.

The following requirements must be included in your quote:

WARRANTY

INSTALLATION & TRAINING

MAINTENANCE

QUOTE ALL YEARS

The government intends to award one or more firm-fixed priced (FFP) purchase order(s) to the offeror representing the best value to the government based on the evaluation factors listed below. Evaluation factors are listed in order of importance, with most important listed first. The government will conduct a trade-off between price and non-price factors. The Government is not required to award to the lowest priced offeror or the offeror quoting the highest technically rated item.

The government reserves the right to award without discussions.

Evaluation Factors (Listed in order of importance):

1. Technical – Offerors must provide product literature, which demonstrates the capabilities of the quoted item(s). At a minimum the product literature must demonstrate how the quoted item meets the desired specifications outlined above. Information on warranty, maintenance, training, installation and delivery lead-time must be included in the quote submission and will be evaluated. The government reserves the right to utilize technical (i.e., trade magazines) and customer reviews/references as part of the technical evaluation.

2. Price – Offerors must include all applicable costs (Example: Components, Shipping) to include pricing for four (4) one (1) year options for maintenance in their quote. The total quoted price, inclusive of option periods, will be the evaluated price.

In addition to providing product literature, offerors must also submit the completed table below with their quote submission*:

COMPLETED BY OFFEROR

· Absolute quantification of target single DNA or RNA molecules

· State of the art methodology for dye and probe based PCR quantification analysis

· Capacity to partition each sample at least 20,000 fold

· Rapid sample partitioning time (<5 minutes)

· Ability to multiplex sample amplification (at least 48 samples)

· Rapid sample read time (< 30 minutes)

· Rare event detection (1 in 10,000)

· Ability to assay from SYBR-based reactions

· Does not require calibrating sample

· Utilizes consumables from various sources

· Multi-User platform

Applications Supported:

· Rare DNA target identification and quantification

· Pathogen detection

· Absolute quantification of sequencing libraries

· Digital gene expression analysis for low abundance transcripts

· Genotyping and copy number variation detection

· Next-generation sequencing (NGS)

· Biomarker detection and validation

· Single cell mRNA analysis

*Offerors who fail to provide the completed chart above may be considered non-responsive.

Offerors must also submit the following with their quote:

· Completed copy of provision 52.222-48

· Completed copy of provision 252.204-7007

· Completed copy of provision 252.209-7992

· Estimated delivery lead-time

See attached for provisions and clauses applicable to this requirement.

Quoted items must be new. Quotes for refurbished equipment will not be considered.

Offerors must also indicate in quote where item is manufactured.

Item(s) will be shipped to Bethesda, MD.

Deadlines:

Questions/clarifications regarding this solicitation must be submitted via email to carolyn.randolph@usuhs.edu by May 8, 2015. Any question received after May 8th will not be answered. Questions will not be answered over the phone or submitted by any other means. All questions will be answered in an amendment to the solicitation posted on or around May 13th.

Quote packages are due by 5:00 PM Eastern Local Time on May 27th. Quotes must be submitted via email to carolyn.randolph@usuhs.edu. Quotes will not be accepted by any other means. Late quotes will not be considered.

Quote packages should include a cover sheet that provides the following information:

· Company Name

· Point of Contact, to include email and phone number

· DUNS Number

· Statement that includes acknowledgement of latest amendment number (if applicable)

· Will VISA be accepted for payment (Yes / No)