36A77620Q0163-001.docx

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6640--36A77620Q0163 CODEX Instrument Intent to Sole Source Federal contract opportunity
Solicitation number
36A77620Q0163
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Department of Veterans Affairs Office of Information Service Center

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36A77620Q0163 Attachment Salient Characteristics CODEX.docx

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Salient Characteristics

Akoya CODEX

1. General CODEX is a fluidics control instrument that integrates with existing fluorescent microscopes for synchronizing of Assay and image collection

2. Warranty Requirements

a. Twelve months from date of delivery.

3. Technical Specification and Code Requirements

a. N/A

4. Environmental Features

a. N/A.

5. Features

a. Fluidics instrument automates imaging cycles. For each cycle, three reporters with unique

b. Validated on fresh, frozen, and FFPE samples

c. 40+ biomarkers can be imaged per sample

d. Enables customized panels of up to 40+ antibodies combined in a single tissue staining reaction, until all antibodies have been imaged.

e. Includes reagents and software

f. Small size allows for placement on a standard countertop

g. Uses antibodies conjugated to a proprietary library of oligonucleotides

h. Instrument Management software controls the fluidics platform; integrates with the microscope control software for image capture.

i. Analysis manager formats raw images for downstream analysis

j. Key functionalities include drift compensation, background subtraction, cell segmentation, and clustering

k. Multiplex analysis viewer visualizes fluorescence and cluster data, gates cells, and generates spatial network map.

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