Project Grant W911QY1410005

The University of Pittsburgh was awarded an $827,072 project grant from the Department of the Army Medical Command under the Military Medical Research and Development federal grant program to develop TRAUMACHEK, a field-deployable dielectric coagulometer for comprehensive hemostatic assessment in remote damage control resuscitation. The grant will support the University's work to investigate medical solutions for the battlefield by transforming trauma care through innovative research into remote...

The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research Federal Grant Program (CFDA 93.837), awarded a $1,249,317 project grant to Sanaheal Inc. to optimize and validate a hemostatic bioadhesive paste for coagulation-independent rapid control of bleeding. The objective is to develop this innovative solution to effectively treat high-risk bleeding in anticoagulated or coagulopathic patients, which addresses the limitations of existing hemostatic agents....

This $240,412 Project Grant award from the National Science Foundation (NSF) Engineering Program (CFDA 47.041) supports collaborative research at East Carolina University (ECU) to investigate how tension affects the digestion of blood clots. The research aims to test hypotheses about how inherent and applied tension on fibrin fibers impact the fibrinolysis process, which is essential for the proper dissolution of blood clots to prevent risks like strokes and heart attacks. The...

The University of Washington was awarded a $507,517 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The goal of this 4-year grant is to develop novel, synthetic therapies for stabilizing trauma victims in the critical "golden hour" after injury. The key objectives are to create low-volume resuscitants that can provide fluid...

This $234,000 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to engineer hemostatic red blood cells (T-RBCs) for the treatment of acute non-compressible hemorrhage. The primary objectives are to: 1) engineer T-RBCs that can bind to collagen and fibrin, 2) test the ability of the T-RBCs to enhance clot formation and stability in vitro, and 3) evaluate the circulation time, clot binding, and...

This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, is funded under the Cardiovascular Diseases Research program (CFDA 93.837). The $2,315,968 award supports a 4-year research project to develop a novel hemodynamic metric called Tissue Perfusion Pressure (TPP) for improved management of circulatory shock in critically ill patients. The key objectives are to investigate the physiology of TPP in preclinical animal...

The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. received a $1,427,150 cooperative agreement award from the Department of the Army Medical Command on September 15, 2021 to complete work by September 14, 2025. The award supports research under the Military Medical Research and Development program (CFDA 12.420) to investigate blood flow restriction therapy for the postoperative rehabilitation of anterior cruciate ligament reconstruction with quadriceps tendon...

Case Western Reserve University will receive $2,178,081 over four years from the Department of the Army Medical Command under the Military Medical Research and Development program to develop TRAUMACHEK, a field-deployable dielectric coagulometer for comprehensive hemostatic assessment in remote damage control resuscitation. The device will help evaluate trauma patients' coagulation status near the point of injury to facilitate rapid treatment decisions in emergency situations where...

The University of Maryland, Baltimore received a $308,821 Project Grant award from the Defense Health Agency under the Military Medical Research and Development federal grant program (CFDA 12.420). The grant will fund the development of a novel medical device called the TRANSESOPHAGEAL AORTIC BLOOD FLOW OCCLUDER to control non-compressible torso hemorrhage from January 15, 2022 to January 14, 2024. The device aims to transform trauma care for service members and the public through innovative...

This $1,199,991 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program aims to develop novel technologies for real-time assessment of blood clot properties to improve stroke treatment. The key products and services under this grant include: Integration of a sub-millimeter Raman fiber probe into a catheter for intravascular, in-vivo measurement of clot chemical composition. Training of a convolutional neural network to...