This $830,975 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) supports the Training Core for the San Diego Regional Network Award for Kidney, Urologic, and Hematologic Research Training. Over a 5-year period starting September 2024, this collaborative effort between UC San Diego, Scripps Research Institute, and San Diego State University will recruit and train 10 outstanding...
This Project Grant award for $108,000.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant aims to enable medical students at the Medical University of South Carolina (MUSC) to participate in high-quality research on gastrointestinal (GI) and liver diseases during their medical school training. Specifically, the grant will (1) provide a focused...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $516,648 to The Leland Stanford Junior University to conduct research on understanding the mechanisms by which microbially derived metabolites regulate host gut inflammation. The award period runs from August 28, 2024 to February 28, 2027. The research aims to determine the regulatory...
This Project Grant award, totaling $216,736.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research project aims to identify the mechanisms by which the host circadian clock and gut microbiome regulate mucus production in the large intestine to protect against infectious and chemical colitis. Key objectives include determining the specific microbiota...
This Project Grant award of $224,088 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to train a postdoctoral fellow in experimental technologies and conceptual knowledge to become an independent academic researcher in gastrointestinal stem cell biology. The research will elucidate the mechanisms of Notch signaling in immature and adult intestinal stem cells that regulate stem cell and Paneth...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $108,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Regents of the University of Michigan. The grant, titled "MICHIGAN SUMMER UNDERGRADUATE RESEARCH EXPERIENCE: DIABETES & METABOLIC DISEASES", will provide a 5-year summer research experience for 14 undergraduate students per year to instill an appreciation and passion for...
This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $747,500.00 to support research on memory formation in the enteric nervous system (ENS). The project aims to build the tools required for studying the formation and meaning of ENS memories, and then use these tools in combination with various perturbations to transform the...
This federal Project Grant award of $151,643, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research on developing and evaluating Proteolysis Targeting Chimeras (PROTACs) to stabilize hypoxia-inducible factors (HIFs) as a potential therapeutic approach for inflammatory bowel disease (IBD). The principal investigator, Dr. Ornelas Sanchez, and his...
This Project Grant award of $168,900 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research to determine how the commensal bacterium Blautia activates signaling in gut epithelial cells to benefit host metabolism and mucosal health. The research aims to identify the synthetic processes and microbial products of Blautia that augment activation of enteroendocrine...
This Project Grant award, totaling $184,572 and provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research, aims to characterize the transmural nature of ulcerative colitis (UC) and its associated disease-related outcomes using intestinal ultrasound. The research will test the hypothesis that transmural structural alterations to the bowel wall in UC lead to poor clinical outcomes compared...