Project Grant SB1HL184525
- The National Heart, Lung, and Blood Institute awarded Fastline LLC $306,383 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and test a second-generation one-handed central venous line (CVL) placement device. Fastline is engineering a simplified CVL insertion device that enables operators to perform all steps of central vein access—needle puncture, aspiration/injection, manometry testing, and guidewire placement—with a single hand while...
- The National Institutes of Health National Heart Lung and Blood Institute awarded Nimble Surgical Incorporated $314,362 on September 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop FLEXLOCK, a manually operable anchoring guide catheter designed to simplify transradial complex percutaneous coronary interventions. FLEXLOCK delivers simultaneous active and passive support through an anchoring tip to provide stable coronary access during complex PCI...
- The National Heart, Lung, and Blood Institute awarded MDC Studio, Inc. $309,813 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop an automated vascular access device that enables less-experienced providers to safely and reliably perform central venous and arterial cannulation. The R61 phase focuses on automating the core steps of successful cannulation. MDC Studio will design, construct, and test sensors and automation to detect blood vessel...
- The National Heart, Lung, and Blood Institute awarded Bridgesource Medical, Corp. $320,727 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a right heart catheter device that uses pressure-volume loop analysis to identify which patients with tricuspid regurgitation will benefit from percutaneous valve repair procedures. The device addresses a critical clinical gap in patient selection for tricuspid valve interventions. Approximately 1.5 million...
- The National Heart Lung and Blood Institute awarded Venostent, Inc. $1,016,974 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to support pilot-scale synthesis and commercialization of SelfWrap, a bioabsorbable perivascular wrap designed to improve outcomes in arteriovenous fistula creation and other vascular surgeries. SelfWrap addresses the high failure rate of arteriovenous fistulas (AVFs) created for hemodialysis access. Veins used in AVF surgery are...
- The National Heart, Lung, and Blood Institute awarded Aust Development, LLC a Phase I Small Business Innovation Research project grant of $626,604 on September 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837). Aust Development will develop a novel 3D pre-shaped delivery catheter platform to enable precise identification and safe delivery of cardiac conduction system pacing leads. The delivery system will allow physicians to sequentially map the septal myocardium, fix...
- The National Heart, Lung, and Blood Institute awarded Ram Medical Innovations, Inc. $344,740 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop foundational engineering and preclinical data for a coronary sheath stabilization device. The Coronary M-Y Sheath is designed to address limitations in complex percutaneous coronary interventions by providing active stabilization through a proprietary anchoring mechanism that leverages two vascular access...
- Percassist Inc. received a $663,129 Project Grant award from the National Heart Lung and Blood Institute of the Department of Health and Human Services. The award was made under the Cardiovascular Diseases Research program (CFDA 93.837), which supports heart and vascular research. The grant funds the development of a percutaneous ventricular assist device for chronic heart failure patients. Specifically, Percassist will design and test a balloon catheter implant that can be delivered minimally...
- The National Institutes of Health National Heart, Lung, and Blood Institute awarded The Leland Stanford Junior University $737,415 on August 17, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to examine the association between hospital market competition and inappropriate vascular surgical care in older adults. The recipient will conduct a research study analyzing overtreatment patterns in two conditions: abdominal aortic aneurysm (AAA) repair at small sizes not supported...
- The National Heart, Lung, and Blood Institute awarded Nytricx, Inc. $314,337 on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to engineer nitric oxide-releasing intravascular catheters with solid slippery surfaces designed to combat infection and thrombosis in short-term applications. Nytricx, Inc., a self-certified small disadvantaged business headquartered in Athens, Georgia, specializes in nitric oxide release polymer technologies for advanced medical...
The National Heart, Lung, and Blood Institute awarded Vantis Vascular Inc. (doing business as Crossliner Inc.) $496,437 on September 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to advance commercial readiness of a novel guide extension catheter for complex percutaneous coronary interventions. Vantis Vascular is developing a multi-functional guide extension catheter that combines deeper catheter intubation with a microcatheter leading tip and pre-dilatation balloon to enable safe crossing of severe lesions in tortuous coronary vessels. The device addresses a significant clinical gap: while approximately 70 percent of the nearly one million annual percutaneous coronary interventions performed in the US involve complex cases with calcified lesions, tortuous vessels, and multi-vessel disease, existing guide extension catheters are utilized in only 18 percent of coronary interventions because they cannot access distal tortuous lesions in 28 percent of cases and carry safety risks including coronary artery dissection and thrombus embolization. The Crossliner catheter design enables balloon pre-dilatation followed by seamless stent delivery, intended to improve procedural safety and efficacy while reducing procedural duration, radiation exposure, and stent dislodgement risk. Work is performed in Fremont, California with a period of performance from September 15, 2026, through September 14, 2027. This is a Small Business Innovation Research Phase II award. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/3/26 | ||
| Not listed | $496.4k | 9/1/26 |