Project Grant S10OD040235
- Federal Grant Award Summary The University of Pennsylvania received a $573,005 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire a LUMICKS AVIDION Cell Avidity Analyzer. The award, effective May 15, 2026 through May 14, 2027, funds the purchase and installation of this high-throughput scientific instrumentation platform designed to quantitatively measure cell-cell interaction avidity—a...
- Federal Grant Award Summary The Pennsylvania State University received a $1.00 Project Grant award from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) on May 15, 2025, with a completion date of May 14, 2026. This award supports the acquisition of a LUMICKS C-Trap single-molecule system, an integrated optical trap instrument that combines dual optical tweezers, scanning confocal fluorescence microscopy, and microfluidics...
- Federal Grant Award Summary The University of Pennsylvania received a $406,250 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, through May 31, 2030. The award supports the development of novel hydration-centric molecular simulation techniques designed to advance computational methods for predicting and modulating protein interactions. The research deliverables...
- Federal Project Grant Award Summary The University of Pennsylvania received $749,993.00 in Project Grant funding from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to procure an Olympus FV4000-MPE multiphoton laser scanning microscope equipped with a Spectra-Physics tunable infrared Ti:Sapphire pulsed laser. The award, dated July 15, 2025, with a completion date of July 14, 2026, establishes the first multiphoton intravital...
- Federal Grant Award Summary The University of Florida, Division of Sponsored Research, received a $595,180 Project Grant award from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire an AB SCIEX QTRAP 7500 Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) instrument. The award, dated July 15, 2025, with a completion date of July 14, 2026, funds the purchase of state-of-the-art analytical equipment capable of...
- Federal Grant Award Summary The University of Pennsylvania received a $406,250 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 1, 2026 through December 31, 2030. This award supports the development of correlated latent factor models and advanced statistical methodologies for analyzing complex multimodal biomedical study designs. The research addresses a critical gap in current...
- Federal Grant Award Summary The University of Pennsylvania received a $438,609 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective May 7, 2026, with a completion date of February 28, 2031. This award supports the Hammer Laboratory's research combining gene editing technology with traction force microscopy (TFM) to advance understanding of mechanotransduction in leukocyte motility....
- Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the University of Pennsylvania a $616,897 Project Grant on August 8, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award, with a completion date of July 31, 2026, funds development of synthetic intracellular microcompartments designed to enhance immune cell function in immunotherapy applications....
- Federal Grant Award Summary The National Science Foundation (NSF) Office of Integrative Activities awarded $3.98 million to the University of Delaware under the Integrative Activities program (CFDA 47.083) to acquire a 600 megahertz (MHz) solid-state dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) system. The award, obligated on August 15, 2025, with a completion date of July 31, 2028, supports the purchase and installation of advanced analytical instrumentation that will...
- Federal Project Grant Award Summary The University of Pennsylvania received a $406,250 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 2, 2026, with completion targeted for December 31, 2030. This award supports a five-year research initiative to advance nucleic acid chemistry and develop novel xeno nucleic acids (XNAs)—synthetic nucleic acid analogs with modified...
The National Institutes of Health Office of the Director awarded $405,787 to the University of Pennsylvania under the Research Infrastructure Programs (CFDA 93.351) to acquire and install an Asymmetric Field Flow Fractionation-Multiangle Light Scattering (AF4-MALS) system. This integrated analytical platform will be housed within the Johnson Foundation Structural Biology and Biophysics Core and will provide label-free separation and characterization capabilities for macromolecules and nanoparticles, including lipid nanoparticles, adeno-associated viral vectors, protein-nucleic acid complexes, and phase-separated assemblies. The system combines field-flow fractionation technology for size-based separation with multi-angle light scattering for direct molar mass measurement, supplemented by differential refractive index detection, dynamic light scattering, and ultraviolet-visible absorbance capabilities. The AF4-MALS platform will support ten NIH-funded research projects focused on structural biology and nanomedicine, including optimization of lipid nanoparticle formulations for nucleic acid delivery, analysis of protein assemblies and aggregates, and separation of nucleoprotein complexes. The system complements existing analytical infrastructure at the university and will enable orthogonal analytical workflows to advance therapeutic macromolecular formulations and gene delivery technologies. The award period ran from May 1, 2026, through April 30, 2027.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $405.8k | 5/7/26 |