Project Grant S10OD040132
- Federal Grant Award Summary The National Institutes of Health (NIH) Office of the Director awarded the University of South Carolina $749,362 under the Research Infrastructure Programs (CFDA 93.351) to acquire a ZEISS LSM 980 confocal microscope with Airyscan2 capabilities for biological research. The award, effective August 1, 2025, through July 31, 2026, funds the procurement and deployment of advanced microscopy instrumentation designed to replace the institution's aging ZEISS LSM 700...
- The National Institutes of Health Office of the Director awarded the University of South Carolina $394,999 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to acquire an Element Biosciences AVITI24 system for next-generation sequencing and spatial multiomics at the university's Functional Genomics Core. The AVITI24 platform will replace the university's aging Illumina NextSeq 500 and enable integrated spatial transcriptomics and proteomics capabilities...
- Federal Project Grant Award Summary The National Institutes of Health (NIH) Office of the Director awarded the University of Southern California $1,131,640 under the Research Infrastructure Programs (CFDA 93.351) on September 19, 2025, to procure and deploy a Leica Stellaris 8 DIVE/FALCON multimodal multiphoton fluorescence microscope system powered by a Chameleon Discovery NX laser. The instrument will be operated and maintained by the Multi-Photon Microscopy Core at the Zilkha Neurogenetic...
- The National Institutes of Health Office of the Director awarded the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center $750,000 on May 1, 2026, under the Research Infrastructure Programs (CFDA 93.351) to purchase a Leica Stellaris confocal microscope for its centrally managed core facility in Torrance, California. The Stellaris system will replace a 12-year-old Leica SP8 microscope and serve a broad user group of 12 investigators (10 of whom are NIH-funded) conducting...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded the University of Montana $1,328,615 on July 15, 2026, under the Research Infrastructure Programs (CFDA 93.351) to acquire a Leica Stellaris 8 confocal and two-photon hybrid microscope system for the Biospectroscopy Core Research Laboratory (BCRL), a component of the NIH COBRE-funded Center for Biomolecular Structure and Dynamics at the institution. The microscope will replace a Zeiss 880...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded the University of Pittsburgh $516,462 on May 15, 2026, under the Research Infrastructure Programs (CFDA 93.351) to purchase a single integrated Nikon AXR confocal microscope system. The microscope is a four-color confocal system with resonant scanning capabilities, mounted on a motorized inverted stand and equipped with four GaAsP detectors, two with customizable spectral tuning. The...
- The National Institutes of Health Office of the Director awarded $425,494 to the University of North Carolina at Chapel Hill on May 15, 2026, under the Research Infrastructure Programs (CFDA 93.351) to procure a Miltenyi UltraMicroscope Blaze with Lightspeed Mode for placement in the university's Microscopy Services Laboratory in Chapel Hill, North Carolina. The award funds a light-sheet microscope capable of imaging large cleared tissue samples at cellular resolution, designed to replace an...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded Northwestern University $436,640 on May 15, 2026, under the Research Infrastructure Programs (CFDA 93.351) to purchase an AXL Cleared Tissue Lightsheet microscope system for the Center for Advanced Microscopy. The Center for Advanced Microscopy, the only microscopy-based core facility on Northwestern's Chicago campus, serves approximately 750 users from 300 laboratories annually. The facility...
- The National Institute of General Medical Sciences awarded Winthrop University $249,702 on August 5, 2026, to acquire a spinning disk confocal microscope under the Biomedical Research and Research Training program (CFDA 93.859). The Echo confocal microscope will replace a 17-year-old Olympus FV-1000 spectral laser-scanning confocal microscope that has experienced mechanical failure and is no longer serviceable. The instrument will support faculty and student research, student training in classes...
- Federal Project Grant Summary The National Institutes of Health (NIH) Office of the Director awarded $1,769,674 to the University of California, Santa Cruz under the Research Infrastructure Programs (CFDA 93.351) on May 15, 2025, for the acquisition and installation of a Leica Stellaris 8 (LS8) confocal laser scanning microscope. The award funds the procurement of this state-of-the-art fluorescence imaging instrument to replace a 16-year-old Leica SP5 confocal microscope that reached the end...
The National Institutes of Health Office of the Director awarded the University of South Carolina $347,162 on September 1, 2026, under the Research Infrastructure Programs (CFDA 93.351) to acquire a Leica MICA Widefocal Live Cell Imaging System for the Instrumentation Resource Facility at the School of Medicine Columbia. The system delivers widefield speed fused with confocal clarity through a fully automated platform featuring FluoSync spectral unmixing, AIVIA-powered AI pixel classification, and Thunder/Lightning deconvolution. These capabilities enable publication-grade images, rapid three-dimensional reconstructions, and unbiased quantitative analysis via on-stage incubation, automated z-stacking, and seamless pipeline integration. The system is equipped with LED and laser-diode illumination, high-efficiency HYD detectors, and delivers automated acquisition and AI-driven analysis to accelerate imaging throughput. The facility currently operates a single nine-year-old Invitrogen EVOS FL Auto 2 platform as its only live-cell semi-automated imaging capability, limiting resolution, multiplexing, and throughput. Eleven major users supported by 12 NIH, 5 VA, and 5 additional grants conduct research in nanotoxicology, neural-circuit modulation, microbiome-immune crosstalk, metabolic disease, colorectal cancer, ocular repair, myocardial infarction, vascular malformations, axonal regeneration, cancer cachexia, hypertension, and Alzheimer's disease. All projects require multiplex fluorescence and high-resolution imaging of live and fixed tissues across multiple organs. Work is performed in Columbia, South Carolina, with a period of performance from September 1, 2026, through August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $347.2k | 8/24/26 |