Project Grant S10OD040125
- Federal Project Grant Award Summary The University of Missouri System received a $409,158 Project Grant from the National Cancer Institute (Cancer Treatment Research, CFDA 93.395) awarded on August 8, 2025, with a completion date of July 31, 2027. The grant funds research into enhancing anti-programmed death receptor-1 (anti-PD-1) blockade antitumor efficacy through oncolytic virotherapy-mediated tumor microenvironment immunomodulation. The primary research deliverables include the evaluation of...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the University of Missouri System $418,043 under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) for a two-year project grant running from August 1, 2025, through July 31, 2027. The project deliverables center on the design and development of a self-tunable messenger RNA (mRNA) circuit capable of sustained, precise regulation...
- Federal Grant Award Summary The University of Montana received a $1,328,615 Project Grant from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire a Leica Stellaris 8 hybrid confocal and two-photon microscope system. The award, obligated on July 15, 2026, with a completion date of June 30, 2027, will provide advanced imaging instrumentation to be integrated into the Biospectroscopy Core Research Laboratory (BCRL), a...
- Federal Project Grant Award Summary The University of Missouri System received a $486,426 Project Grant from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) effective April 1, 2026, through March 31, 2031. The award funds fundamental research to elucidate the molecular interactions between leukemic stem cells (LSCs) and bone marrow niche cells, specifically N-cadherin-expressing mesenchymal stem cells (N-CAD+ MSCs), to identify therapeutic targets that...
- Federal Project Grant Award Summary The University of Missouri System's Office of Research Administration was awarded $124,978.00 under the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) on July 15, 2026, for the acquisition and deployment of a Nicoya OpenSPR-XT Surface Plasmon Resonance (SPR) instrument at the University of Missouri-St. Louis campus. This instrumentation grant, awarded through the NIH Instrumentation for...
- Federal Grant Award Summary The University of Missouri System received a $425,974 Project Grant award dated March 1, 2026, under the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental research on plant-derived steroidal biosynthetic pathways. The research program, scheduled for completion by December 31, 2030, aims to identify and characterize biosynthetic enzymes that convert plant sterols into...
- Federal Grant Award Summary The University of Missouri System received a $395,414 Project Grant from the National Science Foundation's Division of Behavioral and Cognitive Sciences under the Social, Behavioral, and Economic Sciences program (CFDA 47.075) effective September 1, 2025, through August 31, 2028. The award supports the Archaeometry Laboratory at the University of Missouri Research Reactor (MURR), which provides geochemical and isotopic analyses of archaeological specimens including...
- Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded The Washington University a $598,134 Project Grant on August 5, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop sensing collimator technology for ultrasensitive Single Photon Emission Computed Tomography (SPECT) imaging of targeted radiopharmaceutical therapies. The four-year project, concluding...
- Federal Grant Award Summary The University of Missouri System received a $479,716 Project Grant from the National Science Foundation (NSF) Directorate for Engineering (CFDA 47.041) awarded on October 1, 2025, with an ultimate completion date of May 31, 2028. The project, "Bioionics: Probing Cellular Ionic Attributes Enabled by a Novel Soft Bio-Ionic Transistors," aims to develop innovative soft ionic transistor technology to measure and analyze ionic characteristics of biological cells...
- Federal Grant Award Summary Washington University in St. Louis received a $750,000 Project Grant award, effective May 1, 2026, through the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351). The award funds the partial purchase of a SYMBIA PRO.SPECTA X3 hybrid Single Photon Emission Computed Tomography and X-ray Computed Tomography (SPECT/CT) scanner manufactured by Siemens Medical Solutions USA. This state-of-the-art imaging...
The University of Missouri System received a $1,014,209 Project Grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) awarded on July 1, 2026, for the acquisition and deployment of the TherYQ FlashKnife System at its Columbia, Missouri campus. The FlashKnife System is a dedicated preclinical radiotherapy platform engineered to deliver ultra-high dose rates (≥40 Gy/s) electron beam radiation, enabling flash radiotherapy (FLASH-RT) research—a frontier cancer treatment modality with preclinical evidence demonstrating superior normal tissue sparing and tumor control compared to conventional radiotherapy. The system features validated ultra-high dose rate electron delivery (150-350 Gy/s), robotic targeting flexibility, integrated dual-mode operation supporting both FLASH and conventional radiotherapy protocols, and ultra-high dose rate dosimetry readiness. The instrumentation acquisition will support a multidisciplinary team of National Institutes of Health-funded investigators conducting cancer research across multiple disease and tissue models, including studies on FLASH-immunotherapy for lung cancer, systemic immune effects of FLASH radiotherapy, FLASH effects in heterogeneous and hypoxic tumors using patient-derived organoids, salivary gland tissue sparing, and advanced pulmonary imaging assessments. By providing validated preclinical FLASH-RT research infrastructure, the award addresses a critical technological gap preventing rigorous mechanistic investigation and translational development of FLASH radiotherapy approaches under controlled and reproducible conditions. The project completion date is June 30, 2027.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 7/6/26 |