This Project Grant award of $749,227 from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) to Trustees of Boston University will fund the acquisition of a state-of-the-art three-photon microscopy system with fluorescence and phosphorescence imaging capabilities. This multi-user facility at Boston University's Neurophotonics Center will enable NIH-funded investigators to study deep brain structure and function in vivo, advancing research on normal...
This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $1,759,412 to the Buck Institute for Research on Aging to acquire a Bruker TIMSTOF Flex MALDI-2 mass spectrometry system. This advanced instrumentation will enable spatially-resolved molecular imaging of human and animal tissues and organoids, facilitating ongoing and future research across 18 independent principal investigators from the Buck Institute and seven...
This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $1,089,778 to The Regents of the University of Colorado (CU-Boulder) to purchase a high-resolution liquid chromatography-mass spectrometry system. The new instrument, consisting of a Waters Select Series Cyclic IMS QTOF mass spectrometer, ACQUITY PREMIER UPLC, and ACQUITY HDX Manager UPLC, will support small molecule, biomolecule, and post-translational...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $304,196 to Laser Bioanalytics LLC for the development of a prototype instrument and techniques for photochemical patterning of lipids in tissue sections. The goal is to enable improved mass spectrometry structural analysis and imaging of lipids, which are important cellular components relevant to disease diagnosis...
This $1,574,994 Project Grant awarded by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will fund the acquisition of a high-resolution tandem mass spectrometer to support large molecule structural characterization research at the University of California, Los Angeles (UCLA). The state-of-the-art mass spectrometer, equipped with electrospray ionization and various activation/dissociation methods, will enable advanced analysis of a broad range of...
This $307,754 National Science Foundation Engineering Directorate project grant will fund the acquisition of a Nikon CSU-W1-SORA super-resolution spinning disk confocal microscope for Boston University. The microscope will enable new spatially resolved transcriptomics and multi-scale connectomics research techniques to study gene expression within cells and neural connectivity in brain networks. As a shared resource housed in BU's Photonics Center, the microscope is expected to serve nine...
This Project Grant award from the National Science Foundation (NSF) Office of Integrative Activities (CFDA 47.083) provides $744,396 to Idaho State University to acquire a Laser Ablation - Inductively Coupled Plasma - Triple Quadrupole - Mass Spectrometer (LA-ICP-QQQ-MS) system. The instrument will enable advanced materials analysis and diverse multidisciplinary research in areas such as archaeology, biological sciences, environmental sciences, forensic anthropology, and geosciences. It will...
This $151,080 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will be used to acquire a circular dichroism (CD) spectropolarimeter instrument by the University of Massachusetts Dartmouth. The instrument will enhance the university's biomedical research and education capabilities in areas such as investigating the structures of chiral nanoparticles and biomolecules. This specialized equipment...
This $949,116 Project Grant awarded by the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) will fund the acquisition of a Thermo Fisher Scientific Orbitrap IQ-X mass spectrometer system with a Vanquish Flex UHPLC system at the University of South Florida (USF). This cutting-edge analytical instrumentation will establish a unique omics capability at USF to support detailed, high-resolution structural analysis of low-level small molecules in complex...
This $2,998,500 project grant from the National Institutes of Health's Office of the Director through the Research Infrastructure Programs (CFDA 93.351) will fund the purchase of a cryoprobe-enabled Bruker Avance NEO 500 MHz NMR spectrometer. The spectrometer will be installed at Boston College's Magnetic Resonance Center to replace aging equipment and enhance research capabilities. As the sole provider of high-field NMR services for Boston College faculty, 67% of whom conduct NIH-funded...
This Project Grant award of $316,012, provided by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351), will fund the acquisition of an Iridia 1kHz excimer laser ablation (LA) system for the Boston University Center for Biometallomics (CBM). The new state-of-the-art LA instrument will enable ultrafast, high-resolution multi-elemental mapping of clinical and preclinical biospecimens using hyphenated laser ablation-inductively coupled plasma time-of-flight mass spectrometry (LA-ICP-TOF-MS). This advanced analytical capability will accelerate NIH-funded research on Alzheimer's disease, neurological disorders, cardiovascular disease, and other biomedical areas by 11 major and 4 minor users across multiple institutions. The award period is from August 1, 2025 to July 31, 2026.