This $2,000,000 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351 - Research Infrastructure Programs) will fund the acquisition of a next-generation Siemens 7 Tesla (7T) whole-body magnetic resonance imaging (MRI) system at the Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital. This new 7T MRI system will replace the research center's existing 22-year-old prototype 7T scanner, providing...
The National Institutes of Health (NIH) Office of the Director awarded The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), a $2,000,000 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to upgrade the hospital's preclinical 14T magnetic resonance imaging (MRI) system with a new 15.2T Bruker magnet. This upgrade will support over 20 NIH-funded research projects at MGH, enabling cutting-edge neurovascular dynamics studies, advanced...
This $2,000,000 Project Grant awarded by the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA #93.351) will enable Yale University to acquire a state-of-the-art 11.7T Bruker preclinical magnetic resonance imaging (MRI) system with cryogenic coil technology. The new ultra-high field MRI scanner will replace an obsolete 20-year old system, providing significantly enhanced sensitivity and resolution to support advanced functional,...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will provide $600,000 to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to purchase a next-generation 3 Tesla human MRI scanner. The new instrument will replace an outdated and obsolete 16-year-old MRI scanner at MGH's Integrated PET-MRI Facility at the Athinoula A. Martinos Center for Biomedical Imaging. This...
This $2,000,000 Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) will provide funding to The Washington University in St. Louis to acquire a new 15.2-Tesla small-animal MRI scanner. This state-of-the-art equipment will replace the university's aging 11.74-Tesla scanner, which has become unsustainable due to high liquid helium consumption costs. The new 15.2-Tesla scanner will offer significantly improved signal-to-noise...
This $2,998,500 project grant from the National Institutes of Health's Office of the Director through the Research Infrastructure Programs (CFDA 93.351) will fund the purchase of a cryoprobe-enabled Bruker Avance NEO 500 MHz NMR spectrometer. The spectrometer will be installed at Boston College's Magnetic Resonance Center to replace aging equipment and enhance research capabilities. As the sole provider of high-field NMR services for Boston College faculty, 67% of whom conduct NIH-funded...
The National Institutes of Health (NIH) awarded a $1,352,820 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to acquire a novel Orbitrap Astral mass spectrometer. This high-performance mass spectrometer will enable high-throughput, high-sensitivity proteomics research focused on advancing the understanding and treatment of cancer and Alzheimer's disease. The grant, awarded on...
The National Institute of General Medical Sciences (NIGMS) awarded a $599,733 Project Grant under the Biomedical Research and Research Training Program (CFDA 93.859) to Florida State University (FSU) to develop a new technology pathway towards 1.5 GHz 1H NMR. The project aims to build a 28.2 T (1.2 GHz 1H)/1PPM, all-superconducting NMR demonstrator magnet using coils of high-temperature superconductors (HTS) Bi-2212 and Bi-2223 nested inside an existing wide-bore, 12 T low-temperature...
This Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $1,211,143 to the University of Pittsburgh to acquire a state-of-the-art 700 MHz NMR spectrometer with a cryogenically cooled probe. This instrument will replace an aging 20-year-old system, enabling the university's Department of Structural Biology to reliably acquire high-quality, high-sensitivity spectra for biomolecular structural and dynamics analysis...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,360,447.52 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), with a project period from Sep 1, 2024 to Aug 31, 2027. The grant funds the development and evaluation of an inexpensive, lightweight "brain monitor" device using...
This $2,000,000 Project Grant awarded by the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) will fund the replacement of a 14T high-field vertical-bore NMR spectrometer and microimager magnet at Massachusetts General Hospital (MGH). The existing magnet, which has been in operation for over 21 years, exhibits high helium consumption rates that are unsustainable. The grant will support the acquisition of a modern 14T Bruker magnet, which will reduce helium consumption by a factor of four and provide another two decades of operation. This specialized research equipment is a critical resource that has supported numerous biomedical research projects at MGH across diverse fields, including MR contrast agent development, tissue pathology, cancer, and neurodegenerative disease studies. The new magnet will ensure the continued availability of this important research infrastructure, enabling MGH to maintain its leadership in hospital-based magnetic resonance research.