The National Institutes of Health (NIH) Office of the Director awarded a $1,722,700 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to Yale University to acquire a state-of-the-art preclinical positron emission tomography/computed tomography (PET/CT) imaging system. This system will enhance preclinical imaging research capabilities at the Yale PET Center, supporting 19 NIH-funded investigators across multiple departments studying areas such as oncology, cardiology,...
This $609,250 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) will support the acquisition of a new automated multi-run Carbon-11 radiochemistry synthesis system for the Vanderbilt University Institute of Imaging Science's Radiochemistry Core Facility. The new system will augment the facility's existing capacity to manufacture Carbon-11 radiotracers, which are extensively utilized in preclinical...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $277,033 to the University of Cincinnati to develop novel approaches for introducing radiolabeled trifluoromethyl groups into PET tracers. The key objectives are to: 1) create a general strategy to transform alkyl halides into alkyl-[11C]CF3 and alkyl-[18F]CF3...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under CFDA Program 93.286 "Discovery and Applied Research for Technological Innovations to Improve Human Health", supports the development of new radiofluorination methods and prosthetic groups to enable rapid construction of PET tracer analogs. The $122,260 award to the University of North Carolina at Chapel Hill will fund research to develop late-stage direct radiofluorination...
The University of Wisconsin-Madison received a $576,756 Project Grant award from the National Institutes of Health's Research Infrastructure Programs (CFDA 93.351) to purchase a state-of-the-art small animal PET/CT imaging scanner. This new instrument will serve as a shared resource to support NIH-funded cancer research projects at the university, improving the productivity and scientific quality of studies that seek to better understand cancer biology, radiation therapy effects, and the...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $780,034 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Regents of the University of California, San Francisco (UCSF) to develop new chemoenzymatic methods for synthesizing infection-targeted PET radiotracers from the common oncologic tracer 2-deoxy-[18F]-fluoro-D-glucose ([18F]FDG). The goal is to increase access to new PET imaging tools for detecting Staphylococcus...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $505,848.59 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to The Trustees of the University of Pennsylvania for the project "METAL-MEDIATED C-H RADIOFLUORINATION FOR RAPID ACCESS TO PET IMAGING AGENTS". The project aims to develop new methods for rapidly synthesizing Fluorine-18 labeled organic molecules for Positron...
This Project Grant award from the National Cancer Institute (CFDA 93.398 Cancer Research Manpower) provides $665,435 to The Leland Stanford Junior University (Stanford University) to develop the first system capable of simultaneous multi-tracer positron emission tomography (PET) imaging. The project aims to enable the simultaneous imaging of multiple biological processes, such as neuroinflammation, β-amyloid, phosphor-T, and neurodegeneration, which are characteristic of Alzheimer's disease....
This federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $1,899,234 to Vanderbilt University Medical Center (VUMC) to replace their aging MRI and PET scanners with a new integrated MRI-PET system. The award will fund the acquisition of a state-of-the-art 7T MRI scanner and a PET insert with an 80mm axial field of view, enabling simultaneous PET and MRI imaging. This updated scanner system will support over...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $1,149,264 to The University of Texas MD Anderson Cancer Center to develop a rapid, inexpensive microfluidics-based approach for dose-on-demand production of radiopharmaceuticals. The objectives are to: 1) employ a "ship-on-chip" device for isotope...