This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program supports research to develop innovative radiotracer labeling methods for Positron Emission Tomography (PET) imaging. The $277,033 award to the University of Cincinnati aims to establish general strategies for radiolabeling alkyl halides and carboxylic acids with the [11C]CF3 and [18F]CF3 moieties. This work seeks to enable the synthesis of a diverse range of PET tracers incorporating trifluoromethyl groups, which can serve as valuable tools for biomedical research and clinical diagnosis. The 4-year project leverages expertise across the University of Cincinnati's Department of Chemistry and the PET Radiopharmaceutical Sciences division of the National Institute of Mental Health.
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