This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) is providing $1,999,999.00 to the University of Kansas Medical Center Research Institute, Inc. to establish a Midwest Regional Cryo-Electron Microscopy (Cryo-EM) Facility. The funding will be used to acquire a Glacios 200 kV Cryo-TEM equipped with a Falcon 4i detector and Selectris energy filter. This instrumentation will support high-resolution...
The National Institutes of Health (NIH) awarded a $2,851,538 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to the University of Colorado-Denver to upgrade the cryo-electron microscopy (cryo-EM) capabilities at the Anschutz School of Medicine Cryo-Electron Microscopy Facility (ANCEM). The grant will enable the acquisition of a Thermo Fisher Scientific integrated cryo-EM imaging system, including an imaging energy filter and direct electron detector, to enhance the...
This $656,315 Project Grant award from the National Institutes of Health (NIH) Research Infrastructure Programs (CFDA 93.351) will enable Vanderbilt University to acquire a modern 120kV Transmission Electron Microscope (TEM), the Talos L120C, to support advanced structural biology research. The new TEM will replace two outdated microscopes and enhance the university's cryo-electron microscopy (cryo-EM) workflow capabilities. The Talos L120C will enable high-resolution structural analysis of...
This federal Project Grant award, provided by the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351), will fund the purchase of a Hitachi 7800 transmission electron microscope (TEM) for the Electron Microscopy Core Facility (EMCF) at the University of Colorado Anschutz Medical Campus in Aurora, Colorado. The $678,407 award will enable the EMCF, which serves as a campus-wide, fee-for-service facility supporting basic and clinical science investigators, to...
The National Institute of Standards and Technology (NIST) awarded a $1,250,000 Project Grant (CFDA 11.617 - Congressionally-Identified Projects) to the University of Rochester (UoR) to acquire a Transmission Electron Microscope (TEM). The TEM will significantly enhance UoR's research capabilities and collaboration across scientific and engineering disciplines, including quantum information science, materials science, optics, photonics, and biomedical engineering. The TEM will enable...
This two-year, $219,836 National Science Foundation Integrative Activities Project Grant supports training in cryogenic electron microscopy (cryo-EM) for researchers at the University of Nebraska-Lincoln. The grant enables a research team to acquire hands-on cryo-EM training from experts at the Pacific Northwest Center for Cryo-EM, a user facility operated by Oregon Health & Science University and Pacific Northwest National Laboratory. Upon completing the training, the researchers will...
This National Science Foundation Project Grant of $836,490 supports the acquisition of advanced instrumentation for an in-situ transmission electron microscopy testing facility at the University of Missouri from September 1, 2022 to August 31, 2024. The instrumentation includes a gas-phase test cell with residual gas analyzer, liquid-phase test cell with electrochemical capabilities, and a vacuum cell with heating and biasing capabilities. Additionally, an active image stabilization system...
This $538,834 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) will enable the University of Iowa to acquire a Cytek Amnis ImageStreamX MKII Imaging Cytometer. This specialized instrument will provide NIH-funded investigators and other researchers at the university with access to cutting-edge technology that can generate both qualitative imaging data and quantitative flow cytometry measurements. The...
The National Institute of Standards and Technology (NIST) awarded a $963,000 Project Grant under the Congressionally-Identified Projects program (CFDA 11.617) to San Diego State University (SDSU) to purchase a new Transmission Electron Microscope (TEM) with cryogenic imaging capabilities. This new TEM will replace SDSU's existing obsolete instrument, significantly enhancing the university's biological, chemical, and engineering research capabilities. The grant will fund the base TEM...
This $1,200,000 Project Grant awarded by the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports the development of time-resolved cryo-electron microscopy (cryo-EM) techniques to study the dynamics of diverse biological molecules. The principal investigator and their team at Columbia University will apply this innovative method to investigate the functional cycles of three critical proteins: RNA polymerase, GLP1R, and the multi-drug efflux transporter AcrB....