The General Hospital Corporation Research Management Division, doing business as Massachusetts General Hospital (MGH), received a $2,000,000 Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351). The goal of this award is to purchase a Bruker 15.2T magnet to replace the outdated 14T magnet at MGH's Martinos Center, which has been dedicated to supporting high-resolution anatomical and functional imaging of animals and ex-vivo human brain tissue. This upgrade will boost the translational potential of advanced neuroimaging methodologies, such as single-vessel functional MRI, to bridge cellular and microvascular dynamics from animal to human brain studies. The award will support over 20 NIH-funded research projects focused on mechanistic studies of brain disorders, including Alzheimer's disease, cerebrovascular dementia, and brainstem injury-induced coma, as well as animal organ imaging. The proposed instrument upgrade is expected to accelerate progress on these projects and facilitate the translation of cutting-edge MRI methodologies as a multidisciplinary regional resource for NIH-funded investigators.
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