The New York Structural Biology Center, Inc. has been awarded a $1,995,724 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to acquire a state-of-the-art 800 MHz NMR spectrometer console and associated probes. This instrumentation will enhance the capacity of the existing 800 MHz NMR system to support a range of NIH-funded structural biology research, from fundamental studies of biomolecular...
This $2,998,500 project grant from the National Institutes of Health's Office of the Director through the Research Infrastructure Programs (CFDA 93.351) will fund the purchase of a cryoprobe-enabled Bruker Avance NEO 500 MHz NMR spectrometer. The spectrometer will be installed at Boston College's Magnetic Resonance Center to replace aging equipment and enhance research capabilities. As the sole provider of high-field NMR services for Boston College faculty, 67% of whom conduct NIH-funded...
The National Science Foundation awarded a $1,397,667 Project Grant under its Integrative Activities program (CFDA 47.083) to the University of Denver to acquire a state-of-the-art 600 MHz nuclear magnetic resonance (NMR) spectrometer with a cryoprobe. This instrument will support researchers at the University of Denver and across the Greater Rocky Mountain region, enabling new research ranging from understanding biomolecular interactions to characterizing functional tools in complex biological...
This Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $378,171.00 to Michigan State University (MSU) to acquire a 0.7 mm ultrafast magic-angle spinning (MAS) probe for their 800 MHz NMR spectrometer. This specialized equipment will enhance the university's structural analysis capabilities for macromolecular assemblies, enabling high-resolution characterization of fully protonated and native cellular samples. The...
This $1.97 million Project Grant from the National Institute of Standards and Technology, Department of Commerce, under the Congressionally-Identified Projects program (CFDA 11.617) will fund an upgrade to the nuclear magnetic resonance facility at Rensselaer Polytechnic Institute. The upgrade includes replacing aging and obsolete key parts of an existing nuclear magnetic resonance instrument, including the radio frequency console, cryoprobe, and cryoprobe cooling unit. This facility upgrade...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $1,899,160 to Northwestern University to acquire a state-of-the-art pulsed Q-band electron paramagnetic resonance (EPR) spectrometer. The instrument will be a multi-user shared resource at the university's Integrated Molecular Structure Education and Research Center (IMSERC) facility, accessible to all Northwestern researchers...
The University of California, San Diego (UCSD) has been awarded a $100,000 Project Grant from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to purchase a new 600 MHz NMR spectrometer with a 1.7 mm micro-cryoprobe and 60-sample changer. This instrument will replace a 15-year-old defunct 600 MHz spectrometer that supported UCSD's research programs in marine natural products discovery, structural biology, drug design, metabolomics, and systems biology. The...
The National Institutes of Health (NIH) awarded a $1,600,000 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to Saint Louis University to purchase a high-sensitivity Bruker Q-band ELEXSYS E580 pulse EPR spectrometer. This specialized scientific instrument will enable structural dynamics studies of proteins and their complexes, as well as training for students and researchers. The high-sensitivity pulse EPR spectrometer will support NIH-funded research projects at Saint...
This Project Grant award for $298,000, provided by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) program, supports collaborative research between professors at Southern Illinois University Carbondale and Wayne State University. The project aims to improve the sensitivity of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) through the development of new, cost-effective means of enhancing nuclear...
This $1,200,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports the development of time-resolved cryo-electron microscopy (cryo-EM) techniques to study the dynamics of diverse biological molecules, including RNA polymerase, a G-protein coupled receptor, and a multi-drug efflux transporter. The research, led by investigators at Columbia University, aims to expand the utility of time-resolved cryo-EM for examining molecular...