The National Institute of Mental Health (NIMH) awarded a $2,462,651 Project Grant under its Mental Health Research Grants program (CFDA 93.242) to The Washington University Office of Sponsored Research Services Division. The grant will fund a 5-year project to comprehensively investigate the impact of prioritized mutations known to cause neurodevelopmental and psychiatric disorders using over 100 mouse lines. Through a combination of behavioral analysis, anatomical mapping, and molecular assessments, the project seeks to uncover the spatial and molecular changes in the brain caused by these mutations and their effects on behavior. The effort will coordinate data distribution with other grant recipients and provide a mouse neuropsychiatric disease brain bank to enable replication of findings across the broader research consortium.
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