Project Grant RF1TW013271
- The John E. Fogarty International Center (FIC) of the National Institutes of Health awarded a $220,518 Project Grant to Yale University under the FIC's International Research and Research Training program (CFDA 93.989). The grant, with a project period from Sep 1, 2025 to Jun 30, 2027, will fund research to investigate the relationship between persistent vascular dysfunction and cognitive outcomes among virally suppressed people with HIV residing in low- and middle-income countries. The research...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $414,482 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Virginia Polytechnic Institute & State University (Virginia Tech) on July 24, 2025. The goal of this 2-year project is to enhance the therapeutic efficacy of the Semliki Forest Virus (SFV), a neurotropic oncolytic virus, against glioblastoma, an aggressive form of brain cancer. The project aims to adapt SFV through...
- This Project Grant award from the National Institutes of Health's John E. Fogarty International Center (CFDA 93.989 - International Research and Research Training) provides $5,000 to the University of California, San Diego to discover novel natural products that are potent blood-brain barrier (BBB) permeable inhibitors of the enzyme cathepsin L. The goal is to identify a lead drug candidate that can reduce spinal dynorphin and alleviate chronic pain without the risk of addiction, which is a...
- The National Institute of General Medical Sciences (NIGMS) awarded a $125,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Rector & Visitors of the University of Virginia (UVA) to study the evolution and mechanisms of pathogen avoidance behavior in the nematode host, Caenorhabditis elegans, and its virulent bacterial pathogen, Serratia marcescens. The research aims to examine the interplay between innate and learned pathogen avoidance...
- This $452,769 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to evaluate the impact of the BDGR-49 compound on preventing long-term neurological sequelae caused by Venezuelan equine encephalitis virus (VEEV) infection. The research, conducted by Virginia Polytechnic Institute & State University, aims to determine if BDGR-49 can reduce VEEV replication...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $220,096 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Michigan State University. The objective of this 2-year project, which runs from November 2024 to October 2026, is to elucidate the mechanisms of tetrodotoxin (TTX) biosynthesis in microbial symbionts. The researchers plan to leverage their discovery of TTX-producing bacteria on newt skin to sequence bacterial genomes,...
- The U.S. Defense Health Agency awarded a $737,500 Project Grant to Florida International University (FIU) under the Military Medical Research and Development program (CFDA 12.420) to develop a novel treatment for spinal cord injury-neuropathic pain by targeting fibroblast-derived PI16. The award has a performance period from May 15, 2025 to May 14, 2028. FIU, a Hispanic-Serving Institution and one of the largest minority-serving research universities in the U.S., will leverage its diverse...
- This Project Grant award, valued at $151,200.00, was issued by the Fogarty International Center (FIC) under the International Research and Research Training program (CFDA 93.989) to Mahidol University in Thailand. The award, which runs from September 16, 2025 to August 31, 2030, supports research to characterize the cyclic-di-AMP (c-di-AMP) pathway in the bacterium Clostridioides difficile. The research aims to explore the c-di-AMP pathway as a novel drug target for C. difficile, which is a...
- The National Institute of General Medical Sciences (NIGMS) awarded a $558,490 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Virginia Polytechnic Institute & State University (Virginia Tech) on February 1, 2025. The grant supports Virginia Tech's Initiative to Maximize Student Development (IMSD), a training program that aims to recruit and prepare 25 underrepresented minority doctoral scholars to successfully complete PhDs in disciplines such as...
- The U.S. Department of Health and Human Services' National Institutes of Health (NIH) awarded a $189,672 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to Davidson College in North Carolina. The grant, awarded on August 15, 2025, supports a study titled "Fentanyl and Xylazine Interactions: Toxicity Produced by 'Tranq-Dope'." The project aims to quantify the interactions between fentanyl (a mu opioid receptor agonist) and xylazine (an alpha 2 adrenergic...
The U.S. Department of Health and Human Services' Fogarty International Center (FIC) awarded a $375,392 project grant to Virginia Polytechnic Institute & State University (Virginia Tech) under the FIC International Research and Research Training program (CFDA 93.989). The funding supports a 2-year project (September 2025 to August 2027) to research and develop natural products derived from Mexican millipede secretions as potential new treatments for neurological disorders. The project aims to leverage the unique defensive metabolites produced by millipedes, particularly terpenoid alkaloids, and investigate their potential as neuromodulators for addressing unmet needs in pain management, especially in Mexico where access to existing treatments is limited. This collaborative research initiative aligns with the FIC program's focus on reducing global health disparities through scientific discovery and capacity building between U.S. and international partners.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $375.4k | 9/7/25 |