Project Grant RF1MH141448
- This Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), aims to investigate the role of cortico-striatal circuitry in model-based decision-making. The $189,540 grant, awarded on February 1, 2025, will be used to monitor and manipulate neural activity in the prelimbic cortex and dorsomedial striatum to determine how model-based control, a key decision-making process, is represented in distinct cell types...
- This Project Grant award of $564,556.00 from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) will support research by Rutgers, The State University to determine how cognitive control networks in the brain enable rapid instructed task learning (RITL) abilities in humans. The central hypothesis is that these networks enable RITL through compositional-conjunctive hierarchies that split tasks into reusable representations. The research aims to provide critical...
- This federal Project Grant award of $3,299,818 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program to Yale University. The grant aims to study the neural mechanisms underlying complex social interaction strategies, such as cooperation and reciprocity, using advanced neuroscience techniques including automated behavioral paradigms, video tracking, and wireless neural recording. The research will focus on the roles of the...
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $633,438 to New York University to develop a data-driven framework for real-time neural control using patterned microstimulation in primate prefrontal cortex. The research aims to uncover the principles governing spatial and temporal summation of multi-electrode microstimulation, and introduce a novel input/output control algorithm to predict...
- This Project Grant award of $608,309 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program will support research to understand the role of the claustrum, a poorly understood brain region, in flexible decision-making. The research aims to test whether claustrum neuron activity encodes decision variables in tasks requiring cognitive flexibility, determine if claustrocortical neurons are required for dynamic decision-making and reversal...
- This Project Grant award, valued at $390,687, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award will support research at New York University (NYU) to investigate how the brain regions of the orbitofrontal cortex, dorsal striatum, and basolateral amygdala interact to support belief updating and context-dependent decision making. The researchers will perform simultaneous electrophysiological recordings and use...
- This Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate the role of striatal interneurons in value-based decision making and behavioral control. The $2,693,038 award will be provided over a 4-year period from September 2025 to August 2029 to the Trustees of the University of Pennsylvania. The research aims to systematically examine the contributions of low-threshold...
- This federal Project Grant award from the Trans-NIH Research Support program (CFDA 93.310) of the National Institutes of Health (NIH) Office of the Director provides $1,286,464 over 3 years (9/10/2024 - 9/9/2027) to Rutgers, The State University of New Jersey to develop and apply a novel vector optogenetics technique. This approach enables precisely controlling the firing patterns of individual neurons in the mammalian motor cortex to study the causal relationship between neural population...
- This three-year project grant from the Department of Health and Human Services National Institutes of Health provides $3,555,862 to The Trustees of the University of Pennsylvania under the Trans-NIH Research Support program (CFDA 93.310) to study the interactions between the locus coeruleus-norepinephrine system and the dorsolateral prefrontal cortex in flexible decision-making. Specifically, the researchers will train monkeys on a novel task to quantify how learned expectations and new...
- This National Science Foundation project grant of $625,000 will fund research into the brain network mechanisms underlying task-general cognition and intelligent human behavior from September 2022 to August 2025. Under the federal Social, Behavioral, and Economic Sciences program (CFDA 47.075), Rutgers University, Newark will investigate how dynamic activity flows within cognitive control networks implement intelligent goal-directed behavior across diverse tasks. Researchers will utilize brain...
The federal Project Grant award titled "NEURAL AND COMPUTATIONAL MECHANISMS OF MULTI-OPTION CHOICE IN PREFRONTAL CORTEX" was provided by the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program. The $1,987,812 award to Rutgers, The State University in Newark, New Jersey aims to identify the computations and neural mechanisms involved in economic decisions between multiple options, using a nonhuman primate model. The 4-year project period runs from September 22, 2025 to September 21, 2029 and involves recording neural activity in the ventromedial and orbital prefrontal cortex to understand how the brain compares decision options, as well as using microstimulation to disrupt value-coding activity in these regions. The research seeks to advance the understanding of how the brain organizes real-world appetitive behaviors and how these behaviors change in neuropsychiatric disease.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.0m | 9/22/25 |