Project Grant RF1AG085529
Award Date 9/1/25
Completion Date 8/31/29
Dollars Obligated $2.6M
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
University City, MO 63130, USA
Similar Awards
- This federal Project Grant award of $307,000.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to conduct a single, highly powered study to identify memory processes that are most sensitive to the asymptomatic, preclinical stage of Alzheimer's disease (AD) pathology. The study combines a continuous report item-location associative memory task with advanced behavioral and neural modeling to estimate subtle changes in memory precision that may differentiate healthy...
- This federal Project Grant award of $423,500 from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research into the behavioral, electrophysiological, and pupil-based rhythms of attention and memory in young and older adults. The project will examine attention and memory performance concurrently with electroencephalography (EEG) and pupillometry, with a sample of 75 young and 75 cognitively unimpaired older adults screened for Alzheimer's disease pathology. The goal is...
- This $749,108 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to understand how memory failures lead to decision failures across the lifespan. The research will use computational and neurobiological approaches to measure the influence of different types of memory - item, context, and statistical learning - on decision-making choices. The project will examine these questions in cognitively normal older adults through behavioral tasks,...
- This Project Grant award of $1,851,569 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research investigating the relationship between early brain development and later neurodegeneration associated with Alzheimer's disease (AD). The research aims to test two key hypotheses: 1) brain regions with high plasticity in early life are more susceptible to pathological changes later in life, and 2) the detrimental impact of social determinants of health (e.g., low...
- This federal Project Grant award for $528,876, provided by the National Institute on Aging (CFDA 93.866 Aging Research), supports research to investigate the cis- and trans-genetic regulation of brain transcriptomics and proteomics associated with Alzheimer's disease (AD) and AD-related dementias (ADRD). The key goals of the project are to: Estimate genome-wide cis- and trans-acting quantitative trait loci (QTLs) effects for transcriptome-wide genes and proteome-wide proteins across 4 brain...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) will support a $185,074 research study conducted by the University of California, Berkeley. The goal of the study is to examine how brain network connectivity is associated with Alzheimer's disease (AD) risk, longitudinal pathology accumulation, and aging. The researchers will use positron emission tomography (PET) imaging and resting-state functional MRI (rs-fMRI) to investigate the mechanisms of how...
- This federal Project Grant award of $203,278.00, provided by the National Institute on Aging under the Aging Research program (CFDA 93.866), will fund research to understand the behavioral and neurobiological mechanisms underlying age-related shifts in motivation and their impact on daily life activity participation in older adults. The research will employ a multilevel, multimodal approach, utilizing behavioral, psychophysiological, neuroimaging, and naturalistic assessment methods to...
- This federal Project Grant award of $145,566 from the National Institute on Aging (CFDA 93.866 - Aging Research) is supporting research at the Icahn School of Medicine at Mount Sinai to investigate how the brain accumulates and utilizes "cognitive maps" - internal neural representations that enable flexible behavior and memory recall. The research aims to provide insights into the neuronal coding deficits underlying cognitive decline, with the goal of informing therapeutic...
- This Project Grant award of $106,464 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research at Brandeis University to investigate the associations among monoamine neurotransmitters, tau pathology, and emotional memory in aging. The research aims to use PET imaging techniques to directly measure monoamine synthesis capacity in the locus coeruleus and dorsal raphe nucleus, regions vulnerable to early tau pathology in Alzheimer's disease. The project will explore...
- The National Institute on Aging (NIA), through its Aging Research federal grant program (CFDA 93.866), awarded a $636,342 Project Grant to Trustees of Boston University (doing business as Boston University Medical Campus) to conduct research on normal and pathological brain aging. The grant, with a performance period from August 1, 2025 to April 30, 2030, will support a multiscale modeling and empirical study of progressive myelin dystrophy, loss of synapses, and neuronal hyperexcitability in...
This federal Project Grant award of $2,631,670 from the National Institute on Aging (CFDA 93.866 Aging Research) supports a research initiative at The Washington University to investigate age-related deficits in episodic memory. The project aims to determine how aging distinctly affects the content and structure of memory representations, and how this relates to dysfunction in different brain networks based on susceptibility to Alzheimer's disease pathology. The research will utilize plasma biomarker status to identify unique cognitive and neural targets for characterizing, assessing, and potentially treating Alzheimer's disease in at-risk older adults. The award period runs from September 1, 2025 to August 31, 2029.
Generated 10/21/25, 6:20 AM
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.6m | 8/27/25 |