The National Heart, Lung, and Blood Institute (NHLBI) awarded a $2,709,341.45 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The Trustees of Columbia University in the City of New York to conduct a 1-week daily diary study. The study aims to estimate the influence of intersectional anticipated and vicarious stigma on home blood pressure, and examine potential mediating mechanisms such as salivary stress biomarkers and anxiety. The research will recruit a...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $147,486 to The Medical University of South Carolina to investigate the mechanisms linking stress and aortic pathology. The research aims to: 1) Examine the role of sympathetic overactivation, TGF-β signaling, and novel pathways in stress-induced extracellular matrix (ECM) remodeling, and 2) Evaluate whether the neurosteroid allopregnanolone can suppress...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under CFDA Program 93.837 - Cardiovascular Diseases Research aims to elucidate the mechanisms by which microbial metabolites mediate the impact of early life stress (ELS) on aortic stiffening and endothelial dysfunction, which are risk factors for cardiovascular disease (CVD). The $249,000 award to the University of Alabama at Birmingham will fund research to: 1) identify ELS-mediated factors that regulate the...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $162,000.00 in funding to Northeastern University to conduct research on understanding the impact of the sociopolitical environment on cardiovascular disease (CVD) preventive care utilization among Black and Latinx immigrant adults. The key objectives of this 5-year project are to: 1) estimate trends and associations between...
This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $748,647 to William Marsh Rice University to conduct a longitudinal study exploring food insecurity as a social determinant of cardiovascular health and psychological well-being among Latino immigrants. The study will collect mixed-methods data from 450 Latino immigrants to characterize the relationships between food insecurity, nutrition, inflammation,...
This Project Grant award of $602,358, provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), aims to assess the contribution of epigenetics to cardiovascular risk in African American women. The project will identify epigenetic biomarkers of cardiovascular disease and its environmental determinants, and evaluate if these biomarkers can contribute to risk prediction assessments. The research will be conducted by the...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to optimize an evidence-based physical activity intervention for Latina women who do not meet physical activity guidelines. The $722,190 award to Brown University will integrate components from mindfulness-based stress reduction to improve adherence to physical activity among inactive Latina participants. The study will also rigorously evaluate stress as a...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $120,000 to Northwestern University to establish the feasibility of measuring bereavement-related stress in a naturalistic setting. The study aims to develop personalized measures of stress reactivity, including affective reactivity (changes in negative affect in response to a stressor) and autonomic reactivity (changes in heart rate...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research federal grant program (CFDA 93.837) will provide $161,951 to Emory University to examine the relationship between chronic and daily stressors, dysfunctional eating behaviors, and cardiometabolic risk among adults in Puerto Rico. The research aims to investigate mechanisms by which stressors influence cardiometabolic disease markers, including negative affect and...
The National Heart Lung and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $727,080 Project Grant to the University of South Carolina to investigate the neurogenic mechanisms underlying the relationship between psychosocial stress, postpartum cardiovascular disease, and postpartum depression. The 4-year research project aims to delineate how stress-induced mitochondrial dysfunction in the medial prefrontal cortex contributes to postpartum...