This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), will fund the development and validation of a novel wearable sensor system called "SleepTronix" to comprehensively assess sleep, breathing patterns, and circadian rhythms in individuals with obstructive sleep apnea (OSA). The $253,500 award will be used to refine the SleepTronix system, which monitors physiological signals such as EEG,...
This $332,862 federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports a study to assess night-to-night variability in novel obstructive sleep apnea (OSA) severity metrics and their impact on daytime functioning. The study will leverage cutting-edge sleep monitoring technology and ecological momentary assessments to enroll 300 participants (100 men, 200 women) from two sleep medicine...
The federal Project Grant award R56HL171128, totaling $1,415,112.00 and funded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), aims to evaluate a telehealth-delivered adaptive intervention for persons newly diagnosed with obstructive sleep apnea (OSA) to promote continuous positive airway pressure (CPAP) therapy adherence and improve health outcomes. The primary objectives are to compare the effects of motivational...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $1,534,832 to the University of Pittsburgh to develop accessible sleep EEG growth charts for young people. The project aims to create normative age-based reference models for sleep physiology measures in typically developing individuals aged 9-26 years using both polysomnography and a wearable sleep recording device. This research...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $1,602,357 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to KDH Research & Communication, Inc., a woman-owned small business. The grant will support the development and evaluation of the "Personalized Approach to Habits-Sleep" (PATH-S) mobile app. The PATH-S app aims to improve sleep duration and decrease asthma symptoms in Black teens aged 14-17 with asthma by using gamification and...
This $1,420,164 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to simultaneously evaluate brain oxygen metabolism and upper airway anatomy in patients with obstructive sleep apnea (OSA). The key objectives are to: 1) optimize an MRI protocol to monitor metabolic and structural changes during induced apneas; 2) examine how OSA disease severity impacts oxygen metabolism and airway anatomy in patients during...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research CFDA program (93.837), aims to improve the diagnosis of obstructive sleep apnea (OSA) in primary care clinics. The $740,271 grant, awarded on August 15, 2024, will fund a study to determine the prevalence of undiagnosed OSA and identify barriers to OSA diagnosis in primary care settings. The research will involve two stages: 1) epidemiological assessment of...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $696,470 to the University of Denver to conduct research on the impact of prenatal maternal sleep on offspring cardiovascular disease risk. The 5-year project will objectively measure maternal sleep patterns across pregnancy and evaluate how they relate to maternal biological processes (stress, inflammation), infant growth and adiposity,...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research federal grant program (CFDA 93.837) provides $752,991 to the University of Cincinnati to empirically test the sleep health socioecological framework. The study aims to define how multi-level socioecological factors, including understudied risk factors like racism, housing insecurity, screen media use, and toxic stress, predict inequities in early childhood sleep...
This $821,982 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will support research to investigate sleep variability as a potential new risk factor for cardiovascular disease (CVD) in women. The grant, awarded to The Trustees of Columbia University in the City of New York, will leverage two racially and ethnically diverse cohorts of women to: 1) analyze the link between objectively-measured variable...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), aims to develop a technology-based intervention to improve sleep self-management skills for adults who have experienced a subarachnoid hemorrhage (SAH). The $1,408,372 award will fund the following key activities over a one-year period from September 2024 to September 2025:
Tailoring an existing "Sleep Better" intervention to meet the unique needs of SAH survivors, incorporating enhanced social support and self-management skills to address sleep disturbance and daytime sleepiness. This will be evaluated with 32 SAH survivors and their caregivers.
Developing a technology-based version of the tailored intervention using an iterative human-centered design process with 24 SAH survivors and caregivers.
Refining and testing the usability of the technology-based intervention with 32 SAH survivors and caregivers.
Assessing the overall feasibility and acceptability of collecting primary and secondary outcome measures to further refine the intervention protocol.
The goal is to create a technology-based sleep self-management intervention that can potentially reduce health disparities by providing access to SAH survivors who may have limited access to sleep specialists.