This Project Grant award, valued at $1,432,351.00 and awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to investigate the relationship between exposure to metal mixtures and the risk of coronary heart disease (CHD) across diverse populations. The key objectives of the research are to: 1) evaluate the roles of metals and metal mixtures in CHD risk; 2) assess genetic susceptibility to the effects of...
The Project Grant award of $586,190 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program will support the development of an innovative, in-line autonomous monitoring system for detecting and measuring hexavalent chromium in drinking and groundwater. The project aims to convert a successful feasibility study into a prototype system that can provide rapid, accurate, and calibration-free analysis of chromate contamination over a...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $292,368 Project Grant under the Environmental Health (CFDA 93.113) federal grant program to the Regents of the University of Michigan. The grant, effective September 1, 2024 through March 31, 2026, will support research to "disentangle the drivers and dangers of toxic cyanobacteria biosynthetic heterogeneity in cyanobacterial harmful algal blooms (CyanoHABs)." The goal is to identify the effects of...
The National Institutes of Health National Institute of Environmental Health Sciences awarded a $924,612 Project Grant to the California State University, East Bay Foundation, Inc. under the Environmental Health (CFDA 93.113) federal grant program. The grant will fund research from August 2022 to July 2025 to advance chemical risk assessment and predictive toxicology through the development, validation and integration of high-throughput mechanistic in vitro assays. Specifically, the grantee will...
This Project Grant award, titled "DROSOPHILA NSE5/6: A MISSING LINK FOR HETEROCHROMATIN REPAIR", is funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program. The $456,500 award, effective from April 1, 2025 to March 31, 2027, supports research at the University of Southern California (USC) to identify and characterize the Drosophila NSE5/6 protein and its role in heterochromatin repair mechanisms. The...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program provides $379,504 to the University System of New Hampshire's Keene State College to conduct research on the tissue-specific development of toxicity in response to transgenerational chronic arsenic exposures. The key objectives are to: (1) detect tissue-specific uptake of arsenic in response to transgenerational chronic exposure; (2)...
This Project Grant award of $749,901, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, aims to elucidate the origins of the mutational landscape in cancer. The research project will integrate cellular DNA adductomics, nanopore sequencing, and single-molecule duplex sequencing to investigate how exposure to environmental mutagens, such as 1,2,3-trichloropropane, bromochloroacetic acid, and furan, contributes to the...
This $646,476 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program will support research at the University of California, Los Angeles (UCLA) to investigate how environmental exposure to inorganic arsenic impacts epigenetic regulation and transgenerational inheritance. The overarching goal is to understand how arsenic triggers epigenetic changes that can resist developmental reprogramming in...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $429,504 to New York University (NYU) School of Medicine to characterize human exposure to microplastics during pregnancy. The overarching aim is to leverage existing infrastructure from the NYU Children's Environmental Health Study (NYU CHES) to measure and characterize microplastics in placental tissue collected from the general...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) Federal Grant Program, provides $1,054,600.00 to the Regents of the University of Michigan to study the mechanisms underlying impaired regeneration of alveolar epithelial cells and progressive fibrosis in silicosis and asbestosis. The research aims to define distinct subsets of transitional alveolar epithelial cells, elucidate signaling pathways that prevent...