The University of Minnesota was awarded a $3,972,414 Project Grant from the National Institute of Neurological Disorders and Stroke within the Department of Health and Human Services to develop an electro-optical multiphoton microscope. The microscope will leverage advances in electro-optical beam deflection to enable random-access multiphoton interrogation of neurons and synapses with sub-microsecond access times. This will allow neuroscientists to collect the simultaneous recordings needed...
This $2,156,000 Project Grant award, provided by the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), supports research to develop non-invasive methods for measuring brain oxygen, pH, and carbon dioxide levels. The goal is to better understand the relationship between cerebral blood flow, neuronal activity, and metabolic waste products, which could provide insights into loss of brain function. The research approach combines...
The Regents of the University of Minnesota will receive $4.67 million under a three-year Project Grant from the National Institute on Aging within the Department of Health and Human Services. The grant funds research under the Aging Research program (CFDA 93.866) to characterize neuroplastic changes and their relationship to emerging motor and cognitive deficits in individuals with isolated rapid eye movement sleep behavior disorder (IRBD). Over the period of performance from August 2022 through...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the CFDA program "Discovery and Applied Research for Technological Innovations to Improve Human Health" (93.286), aims to develop a plug-and-play "Any-Nucleus Distributed Active Programmable Transmit (ADAPT)" coil system for ultra-high field (7T) magnetic resonance imaging (MRI). The $641,360 award, granted on July 1, 2025, will enable researchers at the University...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $390,616 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to the Regents of the University of Michigan for the development of layer-specific functional magnetic resonance imaging (fMRI) techniques for clinical 3 Tesla scanners. The goal is to improve signal-to-noise ratio and reduce scan time for layer-specific fMRI, which currently...
The National Science Foundation (NSF) Division of Chemistry awarded a $540,000 Project Grant to the Regents of the University of Minnesota under the Mathematical and Physical Sciences program (CFDA 47.049). The grant supports the development of new radiofrequency (RF) irradiation techniques to enhance the performance of nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI). Specifically, the university's research team is utilizing artificial intelligence software...
This federal Project Grant award, valued at $423,500.00 and awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program, supports research to develop and optimize functional MRI (fMRI) techniques for detecting robust signals in the human nose. The goal is to enable the characterization of functional connections between the nose and the central nervous system, which could aid in...
This Project Grant award of $1,302,368 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) will establish a National Center for Biomedical Imaging and Bioengineering at the University of Michigan. The center will develop microsystems-based imaging technologies, including miniature scanners, actuators, and sensors for fiber-coupled microendoscopes to enable...
The Regents of the University of Minnesota received a three-year, $3.73 million Project Grant from the National Institutes of Health National Institute of Neurological Disorders and Stroke to develop a cranial exoskeleton and pixel-drive system for brain-wide neural recordings and comprehensive behavioral monitoring in freely behaving mice. The grant supports an interdisciplinary team to engineer a six degree-of-freedom cranial exoskeleton capable of manipulating a one-kilogram head stage docked...
The Regents of the University of Minnesota received a three-year, $806,000 Project Grant award from the National Science Foundation Division of Biological Infrastructure. The grant supports the "IIBR INFORMATICS: MINING SPATIAL AND SINGLE-CELL TRANSCRIPTOMES TO UNDERSTAND CELL LOCALITY AND HETEROGENEITY IN TISSUES" project under the Biological Sciences program (CFDA #47.074). The project aims to advance understanding of major biological problems by promoting progress in the...