Project Grant R56DK142290
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $734,612.00 to conduct research on the mechanisms through which stress and obesity reprogram monocyte and macrophage populations in response to elevated glucocorticoid levels. The research aims to elucidate how glucocorticoids induced by early-life stress and diet-induced...
- This federal Project Grant award for $731,850.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to investigate the brain-adipose axis mechanisms that drive the health benefits of time-restricted feeding, with a focus on understanding the role of the circadian SCNAVPADMH neurocircuit in regulating energy expenditure rhythms. The...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $253,500.00 to the Icahn School of Medicine at Mount Sinai to conduct longitudinal single-cell analyses of human islet organoids in response to beta cell regenerative drug therapies. The research aims to elucidate the temporal dynamics and mechanisms by which drugs like harmine,...
- This $769,097 Project Grant was awarded on September 5, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research conducted by the Pennington Biomedical Research Center in Baton Rouge, Louisiana to investigate a novel brain-to-pancreatic islet neural circuit that regulates glucose homeostasis. The research aims to establish the physiological...
- This federal Project Grant award in the amount of $427,000 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to President & Trustees of Williams College. The award is funding a research project to study the role of the parasubthalamic nucleus (PSTN) in regulating feeding behavior and appetite suppression. The key objectives are to determine the afferent...
- This Project Grant award, totaling $502,233, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research conducted by the Regents of the University of Michigan to investigate neuron populations in the nucleus of the solitary tract (NTS) that mediate the aversive and non-aversive suppression of food intake. The research aims to further...
- This federal Project Grant award in the amount of $1,428,186.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Massachusetts. The project aims to investigate the role of CYP4F enzymes in regulating N-acyl amino acid signaling in humans, which has implications for understanding the early...
- This $2,971,227 federal Project Grant, awarded on September 4, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to investigate the role of fatty acids in regulating cellular metabolism and protein synthesis in the context of fasting, inflammation, and metabolic diseases. The research aims to uncover novel signaling pathways through which fatty...
- This federal Project Grant award of $802,843, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research conducted by Yale University to investigate the relationship between intestinal microbial activity and human metabolism. The key objectives are to: 1) understand how insulin resistance affects the adipose tissue lipolysis response to intestinal...
- This federal Project Grant award of $504,705 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, titled "Examining Estrogenic Regulation of Orexin Neurons to Reveal Subpopulations," aims to study the critical regulatory role of orexin neurons in the hypothalamus, which are involved in sleep, energy balance, stress, motivation, and reward...
This federal Project Grant award of $169,000.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant was awarded to the Icahn School of Medicine at Mount Sinai in New York, NY to conduct a research project titled "Defining the Contributions of Amygdalar Circuits to the Metabolic Responses to Homeostatic Challenge." The overarching goal is to improve the understanding of how stress-induced neural signals regulate glucose metabolism and the development of metabolic diseases, with the aim of developing better therapies. The research will involve a detailed analysis of the activity of specific amygdala neural populations in response to stress, determining their physiological roles, identifying genetic markers, and assessing their contribution to metabolic regulation. The award period is from September 5, 2025 to August 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $169.0k | 9/3/25 |