Project Grant R44HL176399
- The U.S. National Heart, Lung, and Blood Institute (NHLBI), through its Cardiovascular Diseases Research program (CFDA 93.837), awarded a $1,364,080 project grant to Vesteck, Inc. on September 15, 2025. The grant supports the development and feasibility testing of Vesteck's novel endovascular suturing device for augmenting endograft fixation during endovascular repair of abdominal aortic aneurysms (AAAs). The device aims to reduce reinterventions due to endograft migration or type 1A...
- The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, awarded a $756,228 project grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of Florida (UF) to develop an AI-enabled model to better predict outcomes for patients with chronic limb-threatening ischemia (CLTI) who undergo revascularization procedures. The project aims to supplement electronic health record and clinical notes data with prospectively collected...
- This $499,103 Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports Alleviant Medical, Inc. in two key efforts: Implementing high-volume manufacturing capabilities and establishing production readiness for the ALV1 system, a novel transcatheter approach to relieve left atrial pressure in heart failure patients without requiring a cardiac implant. Executing reimbursement and marketing initiatives to...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $496,255 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Vivita Technologies, Inc. (Davis, CA) to validate its patented SPEAR Platform™ technology for developing unfixed, immune-compatible, and regenerative xenogeneic biomaterials for transcatheter heart valve replacements. The project aims to produce BARE™ patches derived from porcine pericardium that can avoid immune rejection, integrate with...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $443,544 Project Grant under the Cardiovascular Diseases Research (CFDA 93.837) program to Dasisimulations LLC, a minority-owned small business located in Dublin, Ohio. The grant supports the development and validation of an innovative, AI-driven software platform to automatically perform complex measurements for pre-planning transcatheter aortic valve replacement (TAVR) procedures. The project aims to (1) develop and validate the...
- This $298,368 Project Grant awarded by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development of a novel device for treating mitral valve regurgitation. The project aims to optimize the device design and procedure through bench testing, followed by acute in vivo studies to demonstrate the feasibility of the approach. The funding recipient, Link Medical LLC, has invented a catheter-based technology intended to restore proper mitral...
- This Project Grant award from the National Heart Lung and Blood Institute, under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), provides $464,229 to Limax Biosciences Inc. to advance the development of their HEMOMAX biodegradable hydrogel sealant for use in vascular surgery. The key objectives are to: (1) conduct comprehensive bench performance testing, including sterilization validation and endotoxin assessment, and (2) evaluate the safety and efficacy of HEMOMAX in a...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $699,296 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of North Carolina at Chapel Hill (UNC-CH) to investigate optimal treatment strategies for patients with chronic limb threatening ischemia (CLTI). The proposed research will leverage data from the NHLBI-sponsored BEST-CLI randomized controlled trial to identify patient characteristics associated with different disease...
- The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), awarded a $306,872 project grant to Vena Vitals Inc., a women-owned small business in Irvine, California. The grant funding supports the development of "VeriSleep", a wearable device that can provide continuous, non-invasive monitoring of cardiovascular biomarkers during sleep. The goal is to create a robust, cost-effective solution that can capture...
- The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $1,024,635 project grant to Corvion, Inc. to develop a Totally Implanted Left Ventricular Assist Device (TI-LVAD). The TI-LVAD aims to reduce complications and enhance quality of life for heart failure patients by eliminating the need for a percutaneous driveline and external power supply. The key innovation is a hybrid magnetically levitated blood pump that requires...
The National Heart, Lung, and Blood Institute (NHLBI), through its Cardiovascular Diseases Research grant program (CFDA 93.837), awarded $1,032,585 to Aveera Medical Inc. on September 1, 2025. The funding supports Aveera Medical's project to develop and evaluate their novel Native Deep Vein Arterialization (NDVA) procedure using the Boomerang System. This technology aims to reduce major amputations and improve quality of life for patients with "no-option" chronic limb-threatening ischemia (no-CLTI), a severe form of peripheral artery disease. Aveera Medical has completed early feasibility studies demonstrating the potential for their NDVA procedure to improve limb salvage rates by up to 50% in this patient population, which could translate to 60,000 fewer annual amputations in the U.S. The project will be completed by August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 8/15/25 |