Project Grant R44DK143876
- This $226,192 federal Project Grant was awarded on July 15, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports the development of a novel over-the-scope platform for controlling variceal bleeding, a major complication of cirrhosis that can be life-threatening. The project aims to mate a single-use endoscope technology developed by the awardee,...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through its Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $324,678 Project Grant to Lumina Medical LLC in Culver City, California. The grant supports the development of a Motorized Girth Adjustable Dilator with Dilation and Pressure Measurement for the treatment of anorectal disorders, such as anismus and anal stenosis. This innovative device is designed to improve...
- The U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $356,032 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Minnesota Healthsolutions Corporation, a woman-owned small business, to develop a novel bladder catheterization device. The project aims to create a new method for bladder drainage for the over 1 million Americans, including tens of thousands of children, who have a neurogenic bladder...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $358,039 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Nous Biosciences Inc., a small disadvantaged business located in Pennsylvania. The grant supports research to evaluate a combination therapy of the guanylate cyclase-C agonist dolcanatide and the JAK-STAT inhibitor atiprimod for the treatment of murine colitis. The research aims to explore...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $306,867 project grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Dupage Medical Technology Inc., a minority-owned for-profit organization based in Illinois. The grant aims to develop a new drug treatment for ischemia-reperfusion injury associated with organ transplantation. The project will design a peptide inhibitor and nanoparticle formulation to potently...
- This federal Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is funding the development of an easy-to-operate endoscopic automatic gastroplasty device. The device is designed to mimic the effects of gastric bypass/bariatric surgery for the treatment of diabetes and obesity. The $325,408 award, which began on September 8, 2025, will support...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $1,024,812 Project Grant to Epoulosis Therapeutics Inc. located in Newton, MA. The grant, awarded on August 1, 2025, aims to develop novel treatments for diabetic foot ulceration (DFU) in the form of a wound bandage employing new biomaterials that can release appropriate doses of the drug metrifonate. This is based...
- The U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $372,067 Project Grant to Aleutian Therapeutics, Inc. under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant is for the "Development of an Immune Evasive Stem Cell Line for Type 1 Diabetes Regenerative Therapy." The project aims to develop an immune-evasive stem cell line that could potentially be used in regenerative therapies for type 1...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $708,138 to support the development of a biomechanocompatible small molecule-releasing scaffold for bladder augmentation. The goal is to create an alternative to conventional surgical approaches that use detubularized bowel tissue, which can have significant complications. The...
- The Vanderbilt University Medical Center (VUMC) was awarded a $1,050,000 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will fund a pilot, randomized trial comparing placebo versus antibiotic treatment for acute uncomplicated diverticulitis in 100 patients, with oversampling based on race and ethnicity. The goal is to determine differential...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $1,192,362 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Averto Medical Inc. in Fremont, California. The grant is funding a safety and efficacy clinical trial of Averto's COLOSEAL ICD System, a minimally invasive medical device designed as an alternative to temporary ostomy surgeries for patients with diverticular disease. This innovative technology aims to eliminate the need for temporary ostomies, which carry high morbidity rates and significant healthcare costs. The project is expected to run from September 2025 through August 2027. Successful development of the COLOSEAL ICD System could potentially transform the treatment of diverticular disease and save the U.S. healthcare system up to $7.8 billion annually.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 9/17/25 |