Project Grant R44DK104564

This National Science Foundation (NSF) Cooperative Agreement award under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,250,000 in funding to Biodevek Inc., a Boston-based small business, to develop a novel sprayable hydrogel sealant for managing gastrointestinal (GI) lesions and bleeding. The project aims to create a minimally invasive, bio-adhesive hydrogel solution that can provide sustained lesion protection and hemostasis, potentially reducing...

The National Heart, Lung, and Blood Institute (NHLBI), through the Cardiovascular Diseases Research (CFDA 93.837) federal grant program, awarded a $1,249,317 Project Grant to Sanaheal Inc. for the development and validation of a "Hemostatic Bioadhesive Paste for Coagulation-Independent Rapid Control of Bleeding." The objective is to optimize and validate this hemostatic paste to meet FDA regulatory requirements in preparation for a future pivotal clinical trial and commercialization....

This $250,000 National Science Foundation project grant supports the development of a microneedle-mediated adaptive phototherapy wound dressing by the University of South Florida from October 1, 2022 to November 30, 2024. The dressing integrates self-diagnosis and treatment tailored to wound conditions without external electronics or medical professionals. Microstructured microneedles act as optical waveguides to deliver localized blue or red light therapy at wound sites, changing wavelength...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Gelsana Therapeutics Inc. a $649,984 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) on September 5, 2024. The purpose of this grant is to support the development of Provasliex Gel, a zwitterionic hydrogel that delivers controlled release of platelet-derived growth factor (PDGF) to address impaired wound healing associated with diabetes. The goal is to demonstrate the...

This $962,735 cooperative agreement from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships program (CFDA 47.084) supports the development of an enhanced biodegradable tissue adhesive for gastrointestinal surgical wound closure applications by Bezwada Biomedical LLC. The small business will refine a polyurethane-based adhesive formulation and assess its in vivo performance to identify a safe, easy-to-use lead tissue adhesive that can help prevent anastomotic...

This $100,000 National Science Foundation Technology, Innovation, and Partnerships grant funds the development of tunable porosity aerogel for wound care dressings at The University of Akron from July 1, 2022 to June 30, 2023. The project aims to create a novel bio-based aerogel dressing that could help heal patients with chronic wounds faster by requiring fewer dressing changes. Aerogels' high porosity, surface area and moisture balance properties may create an incubator-like wound healing...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $645,574 to Syntis Bio Inc. to develop an oral pill that mimics the effects of gastric bypass surgery. The proposed product is a gastrointestinal synthetic epithelial lining (GSEL) that forms a semi-permeable barrier in the duodenum to block nutrient absorption, thereby achieving weight loss results similar to...

The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $350,000 Project Grant to Karios Technologies LLC to develop TissueShield, a novel single-use, ready-to-use, sterile, dual-chamber, dual-syringe sprayable hydrogel for preventing post-surgical cardiac adhesions. TissueShield is a 3-component polymer system that can be easily sprayed directly onto the heart, forming a robust anti-adhesion layer within seconds. The...

This Project Grant award of $275,000 from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development and validation of an aerogel-based wound dressing material with integrated fluid management, biofilm prevention, and rapid infection detection capabilities. The awardee, Auxilium Health, Inc., aims to create a novel wound dressing platform that can improve the management of acute wounds, chronic wounds, surgical...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $2,433,408.00 to Global Biomedical Technologies LLC to develop and validate an adhesive acrylic surgical drape for use in negative pressure wound therapy (NPWT) applications. The key objectives are to: 1) Compare the performance of the "Comfort...