The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,000,000 Project Grant under CFDA 93.855, Allergy and Infectious Diseases Research, to Dare Bioscience, Inc., a self-certified small disadvantaged business located in San Diego, CA. The grant supports the development of DARE-HPV, an innovative anti-viral vaginal insert to address the health threat posed by persistent high-risk human papillomavirus (HR-HPV) infections, which are associated with cervical cancers. The proposed Phase II studies aim to optimize and validate analytical assays, conduct comprehensive intravaginal safety and toxicity studies, and evaluate the potential for dermal hypersensitivity and impact on condom integrity. Upon successful completion, Dare Bioscience intends to file for IND status using the 505(b)(2) pathway, with Kaletra as the reference drug. The award period is from December 17, 2024, to November 30, 2026.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $1.0m | 12/17/24 |