Project Grant R43OD037840
- The National Institute of General Medical Sciences (NIGMS) awarded a $324,239 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Ora Biomedical, Inc., a biotechnology company in Seattle, WA. The purpose of this Phase I Small Business Innovation Research (SBIR) grant is to develop "ELEGANTRY", a software and hardware infrastructure to improve rigor and reproducibility in invertebrate research using the model organism Caenorhabditis elegans (C....
- This federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $416,925 to Objective Biotechnology, Inc. to develop and evaluate a miniature, high-performance microscope system for imaging brain activity in freely behaving mice. The award period runs from September 15, 2025 to August 31, 2027. The key objectives are to engineer the "Mini-MScope" device with a highly sensitive imaging sensor, evaluate its...
- This federal Project Grant award of $398,774 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop a strategy for efficient microinjection-free CRISPR/Cas applications in the model organism Caenorhabditis elegans (C. elegans). The project, awarded to North Carolina State University, seeks to address a key limitation in C. elegans genetic manipulation by enabling the effective delivery of...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $263,749 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Sound Innovation LLC in Albany, NY. The grant supports the development of a portable small animal imager to accelerate drug development. The project aims to create a cost-effective and high-quality imaging solution to improve the preclinical stage of the drug development...
- Duke University received a $1,019,484.58 Project Grant award from the National Institutes of Health's National Institute on Aging under the Aging Research program (CFDA 93.866) for the period September 1, 2021 through May 31, 2022. The award will support research using the nematode C. elegans as a model organism to study aging-associated neurodegeneration at the molecular level, with the goals of uncovering novel mechanisms underlying this process and establishing C. elegans neurons as a...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $387,500 Project Grant to The Johns Hopkins University on May 1, 2025. The funding supports a research program that systematically investigates the roles of conserved microRNAs during animal development. The research leverages the experimental system provided by C. elegans, utilizing state-of-the-art molecular biology and genetics approaches. The...
- The University of Washington was awarded a $317,972 Project Grant from the National Science Foundation Division of Biological Infrastructure under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). The two-year grant will support collaborative research and integrated modeling of the Caenorhabditis elegans nervous system. Specifically, the University will conduct comprehensive electrophysiological recording of the nematode's nervous system to develop a...
- This $923,205 federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will enable researchers at the University of Rochester and their collaborators to acquire a state-of-the-art Vevo F2 LZR-X ultrasound and photoacoustic imaging system. This advanced small animal imaging instrument will support a wide range of foundational and applied research projects across diverse disciplines at the university, including medicine,...
- The National Institute of General Medical Sciences (NIGMS) awarded a $275,756 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Rewire Neuroscience LLC, a woman-owned small business in Oregon. The funding supports the development of PipSqueak Pro, an AI-powered computer vision platform that aims to democratize access to advanced machine learning techniques for automated biomedical image analysis. The platform seeks to reduce human bias, subjectivity,...
- This $294,543 Project Grant awarded by the National Institutes of Health's (NIH) Office of Research Infrastructure Programs (ORIP) under CFDA 93.351 supports the development of an automated machine vision-guided robotic system for microinjecting Drosophila (fruit fly) embryos. The funding will allow Objective Biotechnology, Inc. to evaluate the efficacy and generalizability of this "autoinjector" technology for transgenesis across various Drosophila experimental conditions, as well...
The National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) awarded a $246,718 Project Grant (CFDA 93.351) to Geegah LLC, a small for-profit company in Ithaca, New York, to develop and understand gigahertz ultrasonic imaging of the model organism C. elegans. The grant aims to reduce the manual effort involved in C. elegans research and enable automated longitudinal phenotyping of these worms across different laboratories. Through this project, Geegah LLC will utilize its expertise in advanced imaging solutions and high-frequency ultrasonic mapping systems to create analytical and finite element models of the C. elegans anatomy, as well as design an automated probing system to streamline worm research. The project period runs from September 1, 2025, to August 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $246.7k | 8/4/25 |