Project Grant R43NS139812
- This $2,503,949 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Rockefeller University aimed at discovering therapeutic targets for neurological diseases. The project utilizes new techniques and concepts to study the fundamental mechanisms of brain disorders, focusing on how differences in cell-specific RNA regulation contribute to...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $1,375,478 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the J. David Gladstone Institutes in California. This grant funding supports a multidisciplinary research program to study the role of neurovascular dysfunction in neurodegeneration, CNS repair, and glial cell biology. Key research activities include in vivo two-photon and super-resolution...
- This federal Project Grant award of $458,189 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research focused on understanding how specific membrane-remodeling factors regulate oligodendrocyte membrane dynamics and myelination in the central nervous system. The research aims to elucidate the mechanisms by which these factors shape...
- This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,830,581 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program to The Johns Hopkins University. The grant supports in-depth characterization of the mechanism of action of a new macrocycle molecule called RAPIREON, which selectively activates the nuclease activity of the IRE1 protein in the unfolded protein response (UPR) pathway....
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $310,834 to Clemson University to develop a nanoparticle-based platform for targeted, non-invasive delivery of therapeutics to the peripheral nervous system. The goal is to improve treatments for peripheral nerve injuries and diseases by overcoming the blood-nerve barrier that...
- This $196,460 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to characterize the role of the Integrator-Z3 module in regulating neuronal differentiation. The principal investigator will conduct biochemical purification, proteomics, and RNA-sequencing analyses to investigate how the interaction between the Integrator...
- This federal Project Grant award, valued at $147,486, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The purpose of this award is to investigate the function of a ciliary protein in neural development, with a focus on uncovering novel molecular mechanisms involved in synapse formation that may be relevant to neurological disorders. Using C. elegans as...
- This $128,802 Project Grant was awarded on January 6, 2025 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The funding supports a research project by Case Western Reserve University to define the function of a novel insulin-like growth factor binding protein, named Crimpy, in the central nervous system (CNS) development and function. The project...
- This federal Project Grant award of $364,448.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) focuses on investigating the neural functions of glycoprotein sialylation. The research aims to reveal sialylation-mediated mechanisms of glia-neuron coupling, elucidate the role of sialylation in promoting neuronal viability and resistance to oxidative stress, and characterize...
The federal Project Grant award of $485,442 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will fund the development of "ZippinCarriers", a novel delivery platform designed to transport oligonucleotide (ON) therapeutics and other molecules across the blood-brain barrier to treat neurological conditions. The award will enable the awardee, Zippin Bio Corporation, to advance this groundbreaking technology from August 2025 through the ultimate completion date of July 2027. This federal grant supports NINDS' efforts to drive scientific research focused on understanding, diagnosing, and developing treatments for complex neurological disorders that collectively impact over 3 billion people globally.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $485.4k | 7/28/25 |