Project Grant R43NS080387

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a 3-year, $3,582,963 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to Carnegie Mellon University (CMU). The grant supports the development and validation of novel wearable transcranial focused ultrasound (TFUS) neuromodulation transducer array probes compatible with simultaneous electrophysiological recordings in behaving...

The University of Utah received a $2,856,242 project grant from the National Institutes of Health National Institute of Neurological Disorders and Stroke to develop noninvasive targeted neuromodulation techniques. The grant is funded through the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program. Under the award, the University will perform research in non-human primates to determine effective stimulation parameters for modulating deep brain circuits...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $701,011.00 to The Regents of the University of California, San Francisco (UCSF) to conduct research on the underlying mechanisms of low-intensity focused ultrasound (LIFU) neuromodulation. The project aims to systematically map the parameter space of LIFU's impact on...

This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $423,151 to Duke University to develop a new functional brain imaging technology using super-resolution ultrasound. The goal is to create a radiation-free, low-cost system that can noninvasively map deep brain neural activities at high spatial and temporal resolutions. The award period runs from January 1, 2025 to April 30, 2028. The research plan includes three technical thrusts: 1)...

The National Science Foundation (NSF) awarded a $512,275 Project Grant to the University of Utah to develop a focused ultrasound system for the noninvasive repair of damaged neural pathways. The project, funded under NSF's Engineering program (CFDA 47.041), aims to create a therapeutic tool that can modulate neural connectivity in the human brain, with the potential to enable rehabilitation for individuals affected by neurological and mental health conditions. The research team, comprising an...

The National Institute of Mental Health (NIMH) awarded a $215,343 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the Laureate Institute For Brain Research, LLC in Tulsa, Oklahoma. The grant will fund a 2-year research project titled "Dose-Dependent Functional Connectivity Effects of Low-Intensity Focused Ultrasound Applied to Deep White Matter Tracts in Humans." The project aims to define the dose-dependent effects of low-intensity focused ultrasound (LIFU) applied to...

This $764,646 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support a 3-year research project titled "Advancing Non-Invasive Brain Stimulation: A Comprehensive Study of Temporal Interference Mechanisms (CNS-STIM)". The project aims to bridge gaps in understanding how the innovative non-invasive brain stimulation technique...

This Project Grant award from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), supports research to measure the physiological impact of transcranial ultrasound stimulation (TUS) on the human brain using multimodal neuroimaging techniques. The total award amount is $423,500 over the project period from August 1, 2025 to July 31, 2027. The research aims to quantify the hemodynamic, metabolic, and thermal effects of TUS in the visual system,...

This $2,867,935 project grant from the National Institutes of Health National Institute of Neurological Disorders and Stroke, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), will support the development of effective cerebellar output modulation paradigms. The New Jersey Institute of Technology will utilize focused ultrasound and transcranial electrical stimulation to directly stimulate the cerebellar nuclei and indirectly modulate...

This $193,953 Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) aims to develop and apply a novel ultrasonic brain imaging technology called functional ultrasound imaging (FUSI) to study motor activity in behaving infants. The project has two key objectives: 1) to assess the functional organization of the motor system in typically developing infants performing a reaching task using FUSI,...