Project Grant R43HL180095
- The National Heart, Lung, and Blood Institute awarded Sigt LLC $848,381 on September 1, 2026, to develop a clinical-grade intraoperative cardiac pulsed field ablation and lesion assessment system under the Cardiovascular Diseases Research program (CFDA 93.837), a Phase II Small Business Innovation Research project. Sigt LLC will develop a pulsed field ablation lesion assessment system (PFA-LAS) using proprietary high frequency dielectric sensing (HFDS) technology to enable intraoperative...
- The National Heart, Lung, and Blood Institute awarded Coridea, LLC $305,365 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop cooled radiofrequency bronchoscopic lung volume reduction technology for severe emphysema patients. The project addresses a clinical gap in lung volume reduction therapy. Current surgical options reach only a fraction of severe emphysema patients: wedge excision LVR surgery is invasive and limits candidate eligibility, while...
- The National Heart, Lung, and Blood Institute awarded $598,636 to Spheric Bio Inc. on September 25, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop the EMULAATE platform, a patient-specific left atrial appendage occlusion (LAAO) device for stroke prevention in atrial fibrillation patients. Spheric Bio is developing EMULAATE to assemble fully soft, personalized implants directly inside the patient's body through a minimally invasive approach by delivering,...
- The National Heart, Lung, and Blood Institute awarded $293,759 to Coridea, LLC on August 15, 2026, under the Cardiovascular Diseases Research SBIR program (CFDA 93.837) to develop a closed-loop percutaneous stellate ganglion nerve stimulation (SGNS) system for hemodynamic support in septic shock. Coridea will engineer a custom percutaneous neurostimulation lead with imaging-visible electrodes and fixation features to enable stable, reproducible access to the left stellate ganglion during patient...
- The National Heart, Lung, and Blood Institute awarded $351,388 to Barron Associates, Inc. on August 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a noninvasive hemodynamic monitoring tool for heart failure patients. The project addresses the clinical gap in home and hospital monitoring of acute decompensated heart failure by creating a low-cost alternative to invasive right heart catheterization and costly implantable devices. The proposed solution...
- The National Heart, Lung, and Blood Institute awarded Aust Development, LLC a Phase I Small Business Innovation Research project grant of $626,604 on September 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837). Aust Development will develop a novel 3D pre-shaped delivery catheter platform to enable precise identification and safe delivery of cardiac conduction system pacing leads. The delivery system will allow physicians to sequentially map the septal myocardium, fix...
- The National Heart, Lung, and Blood Institute awarded Corvion, Inc. $2,999,968 on August 10, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a novel pediatric left ventricular assist device (P-LVAD) enabling children with end-stage heart failure to discharge home while awaiting heart transplantation or living long-term with the device. This is a Project Grant (SBIR Phase II). Corvion will engineer an implantable, ultra-low-power blood pump combining hydrodynamic...
- The National Heart, Lung, and Blood Institute awarded Starlight Cardiovascular, Inc. $499,952 under the Cardiovascular Diseases Research program (CFDA 93.837) on August 10, 2026, to advance commercialization of a catheter-delivered, adjustable percutaneous pulmonary flow restrictor designed to replace surgical pulmonary artery banding in newborns with hypoplastic left heart syndrome and other congenital heart defects. The flow restrictor addresses clinical limitations of current surgical...
- Percassist Inc. received a $663,129 Project Grant award from the National Heart Lung and Blood Institute of the Department of Health and Human Services. The award was made under the Cardiovascular Diseases Research program (CFDA 93.837), which supports heart and vascular research. The grant funds the development of a percutaneous ventricular assist device for chronic heart failure patients. Specifically, Percassist will design and test a balloon catheter implant that can be delivered minimally...
- The National Heart, Lung, and Blood Institute awarded Bridgesource Medical, Corp. $320,727 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a right heart catheter device that uses pressure-volume loop analysis to identify which patients with tricuspid regurgitation will benefit from percutaneous valve repair procedures. The device addresses a critical clinical gap in patient selection for tricuspid valve interventions. Approximately 1.5 million...
The National Heart, Lung, and Blood Institute awarded Corfigo, Inc. $447,736 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop the HeartPad Cryoablation System, a device for treating atrial fibrillation by performing full-thickness ablation of cardiac tissue from the epicardial surface on a beating heart. The HeartPad leverages liquid helium cooling and high-efficiency heat exchangers to ablate contiguous epicardial adipose tissue and atrial muscle without opening the heart chamber or requiring cardiopulmonary bypass. This Phase I SBIR effort targets intermediate and late-stage atrial fibrillation resistant to conventional catheter ablation, particularly cases involving posterior left atrial substrate complicated by scar, fibro-fatty infiltration, and epicardial adipose tissue coverage. Phase I will demonstrate overall feasibility of the device in preparation for commercialization in the heart rhythm market. The award is classified as a Project Grant under the SBIR program. Performance occurs in Montclair, New Jersey, with a period of performance from September 1, 2026, through August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $447.7k | 9/1/26 |