Project Grant R43GM099349

This Project Grant award from the National Science Foundation's Integrative Activities program (CFDA 47.083) provides $476,440 to the University of South Alabama to acquire a dual inverted selective plane illumination microscopy (diSPIM) light sheet system. The diSPIM system enables rapid, high-resolution imaging of large biological samples with minimal photodamage, allowing simultaneous measurement of intracellular signals and protein localization across complex model systems. This advanced...

The University of Michigan was awarded a $1.8 million project grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs federal grant program to purchase a Leica SP8 confocal microscope. The microscope will support over 30 investigators at the University engaged in diabetes, vision, and retinal research by replacing two aging microscopes in the university's shared imaging facility. The new microscope will provide high-speed resonant scanning...

This Project Grant award, valued at $400,000, was provided by the National Science Foundation (NSF) under its Computer and Information Science and Engineering (CISE) program (CFDA 47.070). The award supports the development of innovative "snapshot computational imaging" systems that leverage recent advances in metaoptics, or optical devices using sub-wavelength nano-structures, to capture multidimensional information about light interactions with the world. The key objectives of this...

This $388,983 federal Project Grant award from the National Science Foundation (NSF) Division of Chemistry's Chemical Measurement & Imaging Program and Chemistry of Life Processes Program supports the development of a new optical microscope by Professor Eric Potma at the University of California, Irvine. The instrument leverages chiral sum-frequency generation (SFG) microscopy to visualize protein structures in cells and tissues without the need for chemical labeling. This label-free imaging...

This $546,494 award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) will enable the University of California, Irvine (UCI) to acquire a high-resolution optical photothermal infrared (OPTIR) microscope system. This new microscope will support cutting-edge scientific research programs at UCI, foster collaborations with California State University Fullerton, and accelerate partnerships with industry. The OPTIR microscope will allow for sensitive,...

The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $300,000 EAGER (Early-Concept Grants for Exploratory Research) project grant to The Research Foundation for The State University of New York (RF SUNY) to establish near-ultraviolet (NUV) coherent anti-Stokes Raman scattering (CARS) microscopy for highly sensitive imaging of native biomolecules. This technology will be applied to develop label-free digital pathology for brain...

This $184,267 project grant from the National Science Foundation's Integrative Activities program will fund the acquisition of a biomolecular imaging system by Ball State University. The imaging system will advance biochemical and molecular biology research projects conducted by at least seven research groups within BSU's Chemistry and Biology departments. It will also be used for research training programs and teaching activities to improve student education. The critical capabilities of the...

This $307,754 National Science Foundation Engineering Directorate project grant will fund the acquisition of a Nikon CSU-W1-SORA super-resolution spinning disk confocal microscope for Boston University. The microscope will enable new spatially resolved transcriptomics and multi-scale connectomics research techniques to study gene expression within cells and neural connectivity in brain networks. As a shared resource housed in BU's Photonics Center, the microscope is expected to serve nine...

This $573,147 National Science Foundation Project Grant through the Integrative Activities program (CFDA 47.083) will fund the acquisition of a Zeiss LSM 900 confocal microscope with Airyscan for Queens College of the City University of New York's Core Facility for Imaging, Cell, and Molecular Biology. The microscope will enhance multidisciplinary research and training at the minority-serving institution by enabling new microscopy courses and outreach activities promoting STEM access for...

This National Science Foundation Project Grant of $255,261 awarded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) will fund the development of optimized extraction and projection optics for ion point sources. Steam Instruments Inc. will demonstrate technology advances in imaging mass spectrometry through this Small Business Innovation Research Phase I project. Specifically, the company aims to markedly improve mass resolving power to separate key mass...