Project Grant R43CA135960

The National Science Foundation awarded a $275,000 Project Grant to Oraliva, Inc. under the Technology, Innovation, and Partnerships program to develop a portable, programmable single cell cytology platform for the early detection of epithelial cancers. The platform will combine microfluidics and artificial intelligence to classify potentially cancerous tissue in near real-time through multiparameter single-cell analysis and automated evaluation. The objectives are to link different clinical...

The National Science Foundation awarded $256,000 to Optave Diagnostics LLC through the Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a prototype endoscopic probe for molecular imaging and diagnosis of cancerous prostate pathologies. The 12-month project grant will support the creation of a medical device using photoacoustic imaging and acoustic lens technology to aid in the detection and diagnosis of prostate cancer. The proposed endoscopic probe offers an alternative...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Beken Bio, Inc. aims to develop a highly sensitive, minimally invasive laboratory test to detect early-stage ovarian cancer by assaying relevant biomarkers on circulating extracellular vesicles in patient plasma. The project will utilize a novel technology to identify key proteins in extracellular vesicles from various ovarian cancer subtypes and employ a machine...

This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $449,996.00 to the Regents of the University of Minnesota to develop a low-cost, portable sensor platform for early cancer detection. The project aims to combine microwave photonics and polymer-based micro-ring resonator technology to create a highly sensitive system for detecting circulating tumor DNA, a key biomarker for non-small cell lung cancer. This innovation promises to make...

The National Cancer Institute (NCI) awarded Oraliva, Inc. a $400,000 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop a novel, low-cost, and fully integrated point-of-care (POC) gynecological screening test. The grant, awarded on September 1, 2025, with a completion date of August 31, 2026, will enable Oraliva to leverage its proprietary AI-linked cytomics-on-a-chip technology (ONC-INCYT) to create a rapid, POC diagnostic tool that can accurately...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,990 to Scorpido Photonics aims to develop a prototype endoscope-based diagnostic system for rapid, non-invasive detection of microscopic tumors. The project integrates plasmonic nanobubble sensors into a medical device platform and standard endoscope to enable instant, optical detection of cancerous tissues during lung cancer diagnostic procedures. The key product is a...

The federal Project Grant award from the National Cancer Institute's Cancer Detection and Diagnosis Research Program (CFDA 93.394) provided $1,164,814 to O2M Technologies LLC to develop an advanced imaging system using pulse electron paramagnetic resonance (PEPR) techniques. The goal is to create a fast and precise method for measuring partial oxygen pressure (pO2) in tissues, which can guide cancer treatment and other medical applications. The project involves establishing the hardware for...

This STTR Phase I project, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, is focused on developing highly sensitive, room-temperature, single-photon detectors based on plasmonic metasurface coherent optical detection technology. The $304,987 award to Clearview Optics LLC aims to address the need for ultrasensitive optical detectors and ranging systems to enable improved information acquisition and perception...

The Department of Energy Office of Science awarded a $200,000 Project Grant to Photonlab of Fairfield, CA for its "NOVEL POSITION SENSITIVE PHOTOSENSOR TECHNOLOGY FOR RARE DECAY AND RARE PARTICLE DETECTION" project. The one-year project period runs from February 14, 2022 to February 13, 2023. Under this award, Photonlab will develop novel position sensitive photosensor technology to support rare decay and rare particle detection, in alignment with the Office of Science Financial...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Lightfinder Inc. aims to develop a silicon photonic optical coherence tomography (OCT) imager for pathology diagnostics. The primary objective is to create a high-performance, portable, and cost-effective imaging solution by integrating all optical components onto a single silicon chip. The research will address key technical challenges such as achieving high...