Project Grant R43AR087245
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded $1.696 million to Poly Orth International on September 15, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award funds translational pre-clinical research and development of a 3D-printed skin and bone integrated pylon (SBIP-3D) for direct skeletal attachment of limb prostheses. The technology, developed by Poly Orth International, integrates with both residual bone...
- The National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded Penderia Technologies Inc. $306,722 on September 19, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to fabricate and characterize a distal femoral fracture fixation plate featuring an implantable, battery-free wireless sensor for intra- and postoperative monitoring of fixation plate strains. The project targets personalized postoperative...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded Biosensics LLC $314,362 under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) on September 1, 2026, to develop digital assessment tools for motor skills in infants and young boys with Duchenne muscular dystrophy using wearable sensors. The project addresses a critical clinical gap: current motor assessment methods (Bayley Scales of Infant and Toddler Development) cannot detect...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded MDS II LLC $299,996 on September 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to develop and commercialize the Rotational Femoral Nail System (RFNS), an orthopedic device designed to prevent and correct rotational malalignment in femoral fractures. The RFNS integrates an adjustable rotational mechanism and goniometer to enable precise intraoperative alignment and...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the University of Arizona $1,149,088 on September 19, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to refine a computational surgical decision tool for vertebral body tethering (VBT), a growth-modulating surgical technique for correcting pediatric spinal deformities. The project develops and validates a patient-specific computational model to predict which children...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded Carnegie Mellon University $1.04 million on April 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to develop and validate a sensorized compression sleeve for muscle-activity monitoring and rehabilitation tracking in patients following anterior cruciate ligament reconstruction. The research investigates capacitive sensing embedded in e-textiles as a tool to...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a Project Grant of $158,555 to the University of Pittsburgh under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to develop and validate a wireless metamaterial interbody fusion cage for real-time assessment of lumbar spinal fusion. The project, awarded September 1, 2025, with an ultimate completion date of August 31, 2027, addresses current limitations in wireless force...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the University of Pittsburgh $299,992 on September 30, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to quantify the mechanical effects of knee bracing and predict its ability to prevent ligamentous injury. The project employs cadaveric specimens and a six-degrees-of-freedom robotic testing system to isolate and measure how knee braces affect the knee under external...
- The National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded Rush University Medical Center $643,185 on June 10, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award funds development of validated, patient-specific computational models to predict polyethylene wear in total shoulder arthroplasty (TSA) and identify modifiable surgical, design, and rehabilitation targets to improve implant...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded Brigham & Women's Hospital Inc. $683,016 on May 8, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to investigate the role of HOX genes in musculo-skeletal development using human induced pluripotent stem cell (IPS)–derived in vitro models. The research employs human IPS-based cell culture systems to study HOX gene function during skeletal muscle and motoneuron...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases, a component of the National Institutes of Health within the Department of Health and Human Services, awarded Thinks Works, PBC $306,346 on September 1, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846, Assistance Listing designation R43). Thinks Works is developing the Resilient Brace, a flexible, adjustable, connected bracing system designed to treat adolescent idiopathic scoliosis. The device features a flexible mechanical column inspired by the human spine that delivers corrective treatment while preserving patient mobility, coupled with a low-profile fabric strapping system that can be concealed under clothing. Unlike current rigid braces that stop curve progression, the Resilient Brace can be configured to attempt correction of the abnormal spinal curve. The system incorporates real-time treatment monitoring to improve patient compliance and effectiveness. A pilot study with an early prototype demonstrated that 14 of 20 adolescent patients experienced reduction in abnormal curvature after wearing the prototype for 20 minutes, addressing the current standard of care's limitations: approximately half of adolescent patients fail to wear rigid braces as prescribed due to discomfort, restrictiveness, usability challenges, and social stigma. Work is performed in Woodinville, Washington, with a period of performance running from September 1, 2026, through August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.3k | 8/31/26 |