Project Grant R43AI120364

The National Science Foundation (NSF) awarded a $550,000 Project Grant under the NSF Technology, Innovation, and Partnerships (TIP) program to the University of California, Los Angeles (UCLA) to develop a rapid, multiplexed diagnostic tool for serological testing of tick-borne diseases (TBDs). This 2-year project seeks to improve blood-based detection of TBDs, including Lyme disease, Babesia, Anaplasma, and relapsing fever, through an innovative point-of-care (POC) serological assay. The goal is...

This federal Project Grant award of $1,176,645.00, granted by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports the development of a highly accurate proteomic diagnostic assay to identify active Borreliosis (Lyme disease) infection with point-of-need collection technology. The grant recipient, George Mason University, will conduct this research in collaboration with a subcontract to The Johns Hopkins University, which will provide...

Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Leland Stanford Junior University a $436,236 Project Grant effective August 1, 2025, through July 31, 2027, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports development of a novel epitaxial graphene-based biosensor to enable rapid and sensitive detection of active Borrelia burgdorferi (Bb) infections, the causative agent of Lyme disease....

The Department of Defense's Defense Health Agency awarded a $1,330,054 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to the Regents of the University of California, San Francisco (UCSF). The grant supports the "CLINICAL VALIDATION AND IMPLEMENTATION OF A HOST-PATHOGEN-BASED DIAGNOSTIC ASSAY FOR EARLY LYME DISEASE AND OTHER TICK-BORNE INFECTIONS" project, with a performance period from July 1, 2024 to June 30, 2027. As a leading academic medical...

Federal Project Grant Award Summary The University of Connecticut Health Center received a $457,875 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025, through June 30, 2027. The award supports biomedical research investigating the role of the RpoS (sigma factor) regulatory protein in the persistence of Borrelia burgdorferi, the spirochete bacterium that causes...

Federal Grant Award Summary Tufts University School of Medicine received a $3.3 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 19, 2025, with a completion date of August 31, 2029. The grant funds research to identify microbial determinants of excessive inflammation and severe Lyme disease caused by Borrelia burgdorferi (BB). The research aims to delineate...

Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Tufts University School of Medicine a $165,000 project grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 1, 2025, with a completion date of June 30, 2027. This award funds the development of an improved transposon mutagenesis system for comprehensive genetic analysis of Borrelia burgdorferi, the causative agent of Lyme disease. The primary deliverables...

Federal Project Grant Award Summary Pearl Diagnostics, Inc. received a $999,316 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 24, 2025. The award supports development and commercialization of a rapid point-of-care lateral flow device (LFD) urine test for diagnosing invasive aspergillosis (IA), a critical public health threat recently designated by the World Health...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support the development of a novel universal rapid test for HIV diagnosis. IGE Immunodiagnostics & Therapeutics, LLC, a minority-owned small business, will receive $294,948 to adapt their existing HIV ELISA test into a 5th generation antigen/antibody combination rapid test format. The goal is to create a simple, rapid,...

Federal Grant Award Summary Yale University received a $461,375 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025 through June 30, 2027. The grant supports systematic identification of molecular interactions between Lyme disease bacteria (Borrelia burgdorferi) and its tick vector (Ixodes scapularis). The primary deliverable involves screening the ISCREAM (I....