Project Grant R43AI112048

This Project Grant award of $211,038 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research at The Johns Hopkins University to investigate a new strategy for controlling mosquito populations. The key focus is on targeting the enzyme iodotyrosine deiodinase, which plays a critical role in protecting insects like fruit flies from the accumulation of harmful halotyrosines that can suppress...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $302,537 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Synvect, Inc. to finalize the development and commercialization of their NextGenSIT technology for Aedes aegypti mosquito control. The objectives of this grant are to: 1) finalize the genetic components for producing competitive, sterile male Ae. aegypti mosquitoes using CRISPR gene knockouts; 2) develop and validate...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), is funding research to develop new tools and technologies for vector control of the Aedes aegypti mosquito, an important disease vector. The key focus is on evaluating conditional and sex-specific lethal systems that can restrict lethal transgene expression and reduce the fitness load on mosquito populations, as...

This National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (CFDA 47.049) Project Grant of $246,620 awarded to The University of Texas at San Antonio (UTSA) will fund the development of novel mathematical models for Wolbachia-based strategies to control mosquito-borne diseases like dengue fever, malaria, chikungunya, and Zika. The multi-stage models will account for the complex transmission dynamics, spatial and temporal heterogeneity, and Wolbachia's biological...

This Project Grant award from the National Science Foundation (CFDA 47.049 - Mathematical and Physical Sciences) will develop an early-warning system to forecast surges in disease-carrying mosquito populations in the United States. The $300,000 award, effective September 1, 2025 through August 31, 2028, will create modeling tools and ensembling approaches to generate 1- to 4-week ahead forecasts of the relative abundance of Aedes aegypti and Aedes albopictus mosquitoes. The forecasts will be...

Farmsense, Inc. received a $275,000 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program. The award supports the development of an automated, digital classification and counting system for mosquitoes to enable more effective vector control. The project aims to create an end-to-end digital platform for mosquito surveillance that can support the work of vector control districts. The platform will leverage real-time insect...

This federal Cooperative Agreement award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $999,479 to Vectech, Inc., a small disadvantaged business, to develop advanced artificial intelligence (AI) methods for automated identification of mosquito species from high-resolution images. The goal is to enable more accessible and scalable vector surveillance data collection to support public health institutions in their...

This National Science Foundation (NSF) Project Grant award, funded under the Social, Behavioral, and Economic Sciences program (CFDA 47.075), aims to investigate the role of human behavior in the dynamics of mosquito-borne diseases such as dengue and Zika. The $100,000 grant, awarded to North Carolina State University (NC State), will support a multidisciplinary research project to understand how individual decision-making around mosquito prevention behaviors impacts disease transmission. The...

The University of California, San Diego (UCSD) was awarded a $500,000 Project Grant from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences (CFDA 47.074) federal grant program. Through this three-year award beginning June 1, 2023, UCSD will investigate olfactory learning and neuromodulation in the Aedes aegypti mosquito vector. The research aims to elucidate the role of dopamine-mediated plasticity in early olfactory circuits and how...

This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $441,502 to the University of Texas Health Science Center at Houston (UTHealth) to advance CRISPR-based genome editing strategies for managing Aedes aegypti mosquito populations. The key objectives are to: 1) design a CAS12 temperature-dependent system that requires only one strain to produce sterile male...