Project Grant R43AA026234

The National Institute on Drug Abuse (NIDA) awarded a $1,873,868 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The Washington University in St. Louis. The grant is for the "Substance Use in Pregnant People - Optimizing Retention in Treatment by Maximizing Opportunities for Management (SUPPORT-MOM)" project, which aims to develop and test the efficacy of contingency management (CM) interventions to improve substance use disorder (SUD) treatment...

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Massachusetts General Hospital a $735,930 Project Grant (R34) on September 23, 2025, under the Alcohol Research Programs (CFDA 93.273) to develop, validate, and conduct an open trial of a large language model (LLM)-based conversational agent for delivering brief alcohol interventions to emerging adults ages 18-29. The project, which runs through August 31, 2028, addresses the critical public health need to expand screening...

Federal Project Grant Award Summary Massachusetts General Hospital (The General Hospital Corporation) received a $226,125 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) award, effective May 11, 2026 through April 30, 2029. The award funds the REINFORCE Trial, a pilot randomized controlled trial designed to establish the feasibility, acceptability, and preliminary efficacy of phosphatidylethanol (PETH)-based...

This federal Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) totaling $945,397 provides funding to the Magee-Womens Research Institute and Foundation, with a sub-award to the University of Pittsburgh, to adapt and evaluate a collaborative care model (CCM) for treating pregnant persons with opioid use disorder (OUD) in low-resource obstetric settings. The key objectives are to: 1) adapt the CCM for rural and low-resource...

Federal Cooperative Agreement Summary Chestnut Health Systems Inc. received a $2.39 million Cooperative Agreement from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded September 15, 2025, with completion targeted for May 31, 2030. The award funds a hybrid Type 2 effectiveness-implementation trial titled "Recovery Management Checkup Scalability and Sustainability (RMC-SS) Hybrid Experiment," which will integrate and...

Federal Cooperative Agreement Summary The National Institute on Drug Abuse (NIDA) awarded a $6.24 million Cooperative Agreement to the University of Texas Health Science Center at Houston under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and evaluate a novel treatment intervention for cocaine use disorder (CUD). The research, which commenced September 15, 2025, and concludes June 30, 2029, combines contingency management (CM)—a evidence-based behavioral therapy...

This Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $844,475 to the University of Alabama at Birmingham (UAB) to test a bundled intervention aimed at increasing treatment uptake for patients with opioid use disorder (OUD) and nonfatal opioid overdoses after emergency department (ED) discharge. The proposed intervention combines telehealth, peer support, buprenorphine prescribing, and linkage to...

Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Massachusetts General Hospital $734,468 on September 23, 2025, under the Alcohol Research Programs (CFDA 93.273) to develop and pilot Social Identity Mapping for Adolescents in Recovery (SIM-AIR), a novel adjunctive intervention module addressing adolescent alcohol use disorder (AUD). The project, which runs through August 31, 2028, will finalize a standardized treatment intervention that...

HEALTHWORKS Assertive Community Treatment (ACT) Program Summary Brattleboro Memorial Hospital, Inc. received a $1.125 million Project Grant award from the Substance Abuse and Mental Health Services Administration (SAMHSA) Center for Substance Abuse Treatment under CFDA 93.243 (Substance Abuse and Mental Health Services Projects of Regional and National Significance), effective September 30, 2025 through September 29, 2028. The HEALTHWORKS ACT program delivers integrated, multidisciplinary...

Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $303,008 to Behavior Change Hub LLC on July 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to develop the Behavioral Health Counseling Competencies Alcohol Use Disorder (AUD) Training Suite. This Phase I/II Fast Track Small Business Technology Transfer (STTR) project addresses the alcohol treatment gap by creating a didactic and interactive simulation-based training program...