Project Grant R41LM015295
- This federal Project Grant award from the National Heart Lung and Blood Institute under CFDA Program 93.837 - Cardiovascular Diseases Research provides $306,872 to Airalux Medical, Inc. to develop a digital incentive spirometry device. The goal is to improve patient adherence and clinical workflows for preventing post-surgical lung complications, which occur in 1 in 20 patients undergoing an overnight hospital stay. The device uses sensors and software to automatically track patient usage and...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $269,922 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Steth X Microsystems Inc. to develop a smart, wearable contact microphone patch for extended and remote monitoring of lung functions. The goal is to create a low-profile, battery-powered wireless device capable of accurately detecting and quantifying adventitious lung sounds as well as breathing abnormalities in patients with respiratory...
- The National Institute of Environmental Health Sciences (NIEHS) awarded Canairy LLC a Project Grant under the Environmental Health (CFDA 93.113) federal grant program. The $324,770 award, which runs from September 2024 to September 2025, supports the development of a stand-alone wearable device to track environmental exposures and assess respiratory functions for patients with chronic obstructive pulmonary disease (COPD). The device will collect data on personal exposure to pollutants and...
- This Project Grant award of $807,067.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support a study to pioneer the quantitative documentation of human respiratory kinematic profiles. The study aims to address a critical gap in contemporary physiological monitoring - the inability to quantify labored breathing, which contains vital prognostic information not captured by conventional monitoring. Building on a recent innovation called ARK...
- This federal Project Grant award of $805,921 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to integrate multi-trait, multi-ancestry, and multi-omic data from massive global biobanks to decipher the genetic mechanisms underlying respiratory diseases like chronic obstructive pulmonary disease (COPD) and asthma. The award, with a performance period from September 2025 to June 2030, will leverage data from over 2 million participants,...
- Precision Theranostics Inc. was awarded a $256,000 Small Business Innovation Research Phase I Project Grant by the National Science Foundation Division of Industrial Innovation. The grant supports the development of a lung health diagnostic test for chronic obstructive pulmonary disease and prognosis-based early intervention from May 1, 2021 to April 30, 2022. The grant falls under the National Science Foundation's Engineering program (CFDA 47.041), which seeks to improve quality of life and...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $422,075 to The University of Iowa to develop an electromagnetic-actuated, dynamic cell culture method for airway epithelial cells. The project aims to prototype a novel "Magniwell-12" system that integrates a porous PDMS membrane, membrane holder, magnetic actuator, and peripheral heat dissipation/control circuits. This will enable dynamic stretch-relax...
- This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program) provides $274,274 to X-Cor Therapeutics Inc., a minority-owned small disadvantaged business in Washington, DC, to develop a novel respiratory dialysis system for treating chronic obstructive pulmonary disease (COPD) patients. The project aims to optimize a prototype that can efficiently remove excess carbon dioxide from the blood of COPD patients, with the goal of...
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), will evaluate the use of mobile devices to extract vital signs to monitor patients with asthma. The $459,127 award to M5 Enterprise, LLC (doing business as Emedical Sentry) aims to improve the detection and management of asthma attacks through remote patient monitoring. The goal is to enhance telehealth by incorporating video-based vital sign...
- This $2,623,234 federal Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) supports the development of a wearable multiplex biosensor system to monitor exacerbation risk in patients with chronic obstructive pulmonary disease (COPD). The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center is the prime awardee, collaborating with researchers at the California Institute of Technology...
This $471,544 Project Grant awarded by the National Institute of Environmental Health Sciences (CFDA 93.879 - Medical Library Assistance) supports the development of novel technologies by Spiromatics, Inc. for the detection and monitoring of obstructive lung diseases such as COPD and asthma. Spiromatics is creating a portable, handheld spirometer with audiovisual coaching capabilities to enhance the assessment and diagnosis of abnormal lung function. The innovative solutions aim to detect an additional 11% of individuals with airflow obstruction who would have remained undiagnosed using traditional methods. The 1-year project, commencing on September 16, 2025, focuses on advancing an easy-to-use, 2-minute lung function measurement approach that is more patient-friendly than current spirometry procedures.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/22/25 | ||
| Not listed | $471.5k | 9/16/25 |